Hierarchical folding-upon-binding of an intrinsically disordered protein.
Sign Up to like & getrecommendations! Published in 2025 at "Nature communications"
DOI: 10.1038/s41467-025-66420-5
Abstract: Intrinsically disordered proteins (IDPs) often undergo folding-upon-binding to their partners via short linear motifs, typically 5-15 amino acids in length. However, a significant proportion of IDPs do not adhere to this paradigm but fold upon… read more here.
Keywords: folding upon; intrinsically disordered; disordered protein; folding intermediates ... See more keywords
Personalized discovery of disrupted pathways and significant genes in preeclampsia based on accumulated normal tissue data
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cancer Research and Therapeutics"
DOI: 10.4103/0973-1482.203603
Abstract: Purpose: This study was designed to identify disrupted pathways in an individual with preeclampsia (PE) using accumulated normal sample data based on individualized pathway aberrance score (iPAS) method. Materials and Methods: Pathway data were obtained… read more here.
Keywords: disrupted pathways; folding intermediates; expression network; tubulin folding ... See more keywords