Structural Characterization of the Early Events in the Nucleation-Condensation Mechanism in a Protein Folding Process.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.7b01540
Abstract: The nucleation-condensation mechanism represents a major paradigm to understand the folding process of many small globular proteins. Although substantial evidence has been acquired for this mechanism, it has remained very challenging to characterize the initial… read more here.
Keywords: folding process; mechanism; folding nucleus; condensation mechanism ... See more keywords
Folding nucleus and unfolding dynamics of protein 2GB1* * Project supported by the Strategic Priority Research Program of Chinese Academy of Sciences (Grant No. XDA17010504) and the National Natural Science Foundation of China (Grant No. 11947302).
Sign Up to like & getrecommendations! Published in 2021 at "Chinese Physics B"
DOI: 10.1088/1674-1056/abbbfa
Abstract: The folding of many small proteins is kinetically a two-state process with one major free-energy barrier to overcome, which can be roughly regarded as the inverse process of unfolding. In this work, we first use… read more here.
Keywords: energy barrier; protein 2gb1; process; folding nucleus ... See more keywords