Indole and Coumarin Derivatives Targeting EEF2K in Aβ Folding Reporter Cells
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DOI: 10.1111/jnc.16300
Abstract: Misfolding and accumulation of amyloid‐β (Aβ) in the brains of patients with Alzheimer's disease (AD) lead to neuronal loss through various mechanisms, including the downregulation of eukaryotic elongation factor 2 (EEF2) protein synthesis signaling. This… read more here.
Keywords: phosphorylation; folding reporter; eef2k; coumarin derivatives ... See more keywords