Protein folding stability and binding interactions through the lens of evolution: a dynamical perspective.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in structural biology"
DOI: 10.1016/j.sbi.2020.11.007
Abstract: While the function of a protein depends heavily on its ability to fold into a correct 3D structure, billions of years of evolution have tailored proteins from highly stable objects to flexible molecules as they… read more here.
Keywords: protein; folding stability; evolution; protein folding ... See more keywords
Folding-stability criteria of thin-film encapsulation layers for foldable organic light-emitting diodes
Sign Up to like & getrecommendations! Published in 2020 at "Thin Solid Films"
DOI: 10.1016/j.tsf.2020.138277
Abstract: Abstract We have investigated thin-film encapsulation layers that can be stable without the occurrence of cracks even when the layer is repeatedly folded with a small radius down to 1 mm. The folding stability criteria were… read more here.
Keywords: film encapsulation; folding stability; thin film; stability criteria ... See more keywords
CHalf: Folding Stability Made Simple.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.2c00619
Abstract: The structure of a protein defines its function and integrity and correlates with the protein folding stability (PFS). Quantifying PFS allows researchers to assess differential stability of proteins in different disease or ligand binding states,… read more here.
Keywords: pfs; chalf; folding stability; stability ... See more keywords
Discovery of the Xenon-Protein Interactome Using Large-Scale Measurements of Protein Folding and Stability.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c11900
Abstract: The intermolecular interactions of noble gases in biological systems are associated with numerous biochemical responses, including apoptosis, inflammation, anesthesia, analgesia, and neuroprotection. The molecular modes of action underlying these responses are largely unknown. This is… read more here.
Keywords: protein folding; scale; large scale; folding stability ... See more keywords
Comparative Analysis of Protein Folding Stability-Based Profiling Methods for Characterization of Biological Phenotypes.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of the American Society for Mass Spectrometry"
DOI: 10.1021/jasms.2c00248
Abstract: Recently, a new suite of mass spectrometry-based proteomic methods has been developed that enables evaluation of protein folding stability on the proteomic scale. These methods utilize chemical and thermal denaturation approaches (SPROX and TPP, respectively)… read more here.
Keywords: protein folding; folding stability; analysis; biological phenotypes ... See more keywords
A microfluidic device for isolating intact chromosomes from single mammalian cells and probing their folding stability by controlling solution conditions
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-31975-5
Abstract: Chromatin folding shows spatio-temporal fluctuations in living undifferentiated cells, but fixed spatial heterogeneity in differentiated cells. However, little is known about variation in folding stability along the chromatin fibres during differentiation. In addition, effective methods… read more here.
Keywords: folding stability; single mammalian; microfluidic device; chromosomes single ... See more keywords