In silico direct folding of thrombin-binding aptamer G-quadruplex at all-atom level
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DOI: 10.1093/nar/gkx1079
Abstract: Abstract The reversible folding of the thrombin-binding DNA aptamer G-quadruplexes (GQs) (TBA-15) starting from fully unfolded states was demonstrated using a prolonged time scale (10–12 μs) parallel tempering metadynamics (PTMetaD) simulation method in conjunction with… read more here.
Keywords: energy; direct folding; folding thrombin; thrombin binding ... See more keywords