VEGFA165 can rescue excess steroid secretion, inflammatory markers and follicle arrest in the ovarian cortex of high A4 cows.
Sign Up to like & getrecommendations! Published in 2021 at "Biology of reproduction"
DOI: 10.1093/biolre/ioab201
Abstract: A population of cows with excess androstenedione (A4; High A4) in follicular fluid, with follicular arrest, granulosa cell dysfunction, and a 17% reduction in calving rate was previously identified. We hypothesized that excess A4 in… read more here.
Keywords: ovarian cortex; secretion; cortex; high cows ... See more keywords
165 Randel Lecture: Androgen Excess Domestic Livestock Models—What can they Tell us About the Mechanisms Underlying Anovulation?
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Animal Science"
DOI: 10.1093/jas/skad068.080
Abstract: Ovulatory disorders are a major factor in female infertility. Our laboratory has identified several populations of cows and a population of sheep that have excess androgen (High A4) in dominant follicles and ovarian cortex cultures… read more here.
Keywords: follicular arrest; androgen excess; ovarian cortex; cortex ... See more keywords