Lnc2300 is a cis‐acting long noncoding RNA of CYP11A1 in ovarian granulosa cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.30872
Abstract: The high level of progesterone and 17β‐estradiol ratio (P4/E2) in follicular fluid has been considered as a biomarker of follicular atresia. CYP11A1, the crucial gene encoding the rate‐limiting enzyme for steroid hormone synthesis, has been… read more here.
Keywords: follicular atresia; cyp11a1; rna; mir 365 ... See more keywords
p-Chloroamphetamine decreases serotonin and induces apoptosis in granulosa cells and follicular atresia in prepubertal female rats.
Sign Up to like & getrecommendations! Published in 2022 at "Reproductive toxicology"
DOI: 10.1016/j.reprotox.2022.04.006
Abstract: Amphetamine derivatives negatively impact serotonin (5-HT) production, which triggers apoptosis in different tissues, depending on the receptor they bind. 5-HT in the ovary stimulates estradiol secretion, a survival factor of granulosa cells. The effect of… read more here.
Keywords: follicular development; female rats; follicular atresia; granulosa cells ... See more keywords
Ufmylation regulates granulosa cell apoptosis via ER stress but not oxidative stress during goat follicular atresia.
Sign Up to like & getrecommendations! Published in 2021 at "Theriogenology"
DOI: 10.1016/j.theriogenology.2021.04.009
Abstract: Follicular atresia is primarily caused by granulosa cell (GC) apoptosis, although the mechanisms are largely unknown. Ufmylation is a recently identified ubiquitin-like post-translational modifier that plays an important role in cell proliferation and apoptosis. The… read more here.
Keywords: follicular atresia; apoptosis; stress; cell ... See more keywords
Differentially expressed genes and gene networks involved in pig ovarian follicular atresia.
Sign Up to like & getrecommendations! Published in 2017 at "Physiological genomics"
DOI: 10.1152/physiolgenomics.00069.2016
Abstract: Ovarian folliculogenesis corresponds to the development of follicles leading to either ovulation or degeneration, this latter process being called atresia. Even if atresia involves apoptosis, its mechanism is not well understood. The objective of this… read more here.
Keywords: atresia; follicular atresia; gene networks; involved pig ... See more keywords
Characterization of Follicular Atresia Responsive to BPA in Zebrafish by Morphometric Analysis of Follicular Stage Progression
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Endocrinology"
DOI: 10.1155/2018/4298195
Abstract: Bisphenol A is an industrial chemical compound, pervasively polluting the environment and diet, classified as an endocrine disruptor because of its interference effects on the endocrine system. In zebrafish, BPA exposure induces follicular atresia. To… read more here.
Keywords: follicular stage; follicular atresia; bpa; stage follicles ... See more keywords
NORHA, a novel follicular atresia-related lncRNA, promotes porcine granulosa cell apoptosis via the miR-183-96-182 cluster and FoxO1 axis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Animal Science and Biotechnology"
DOI: 10.1186/s40104-021-00626-7
Abstract: Background Follicular atresia has been shown to be strongly associated with a low follicle utilization rate and female infertility, which are regulated by many factors such as microRNAs (miRNAs), which constitute a class of noncoding… read more here.
Keywords: 183 182; atresia; follicular atresia; mir 183 ... See more keywords
Integrative Proteomic and Phosphoproteomic Analyses of Granulosa Cells During Follicular Atresia in Porcine
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2020.624985
Abstract: Ovarian follicular atresia is a natural physiological process; however, the mechanism is not fully understood. In this study, quantitative proteomic and phosphoproteomic analyses of granulosa cells (GCs) in healthy (H), slightly atretic (SA), and atretic… read more here.
Keywords: granulosa cells; analyses granulosa; follicular atresia; caspase6 ... See more keywords
Aquaporin-8 transports hydrogen peroxide to regulate granulosa cell autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.897666
Abstract: Aquaporin-8 (AQP8), a member of the aquaporin family, is strongly expressed in follicular granulosa cells, which could affect the hormone secretion level in females. AQP8, as a membrane protein, could mediate H2O2 into cells, thereby… read more here.
Keywords: cell; follicular atresia; h2o2; granulosa ... See more keywords
The TGF-β/SMAD Signaling Pathway Prevents Follicular Atresia by Upregulating MORC2
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms231810657
Abstract: In mammals, female fertility is determined by the outcome of follicular development (ovulation or atresia). The TGF-β/SMAD signaling pathway is an important regulator of this outcome. However, the molecular mechanism by which the TGF-β/SMAD signaling… read more here.
Keywords: tgf smad; signaling pathway; smad signaling; follicular atresia ... See more keywords