Impaired mitochondrial stress response in cumulus cells is associated with increased apoptosis and accelerated follicular depletion
Sign Up to like & getrecommendations! Published in 2018 at "Fertility and Sterility"
DOI: 10.1016/j.fertnstert.2018.07.300
Abstract: OBJECTIVE: Caseinolytic peptidase P (CLPP) mediates degradation of mitochondrial misfolded proteins to maintain homeostasis under metabolic stress. CLPP is a key factor for mitochondrial function and targeted global germline deletion of Clpp results in female… read more here.
Keywords: cumulus cells; accelerated follicular; follicular depletion; stress ... See more keywords
Cognitive changes across the menopause transition: A longitudinal evaluation of the impact of age and ovarian status on spatial memory
Sign Up to like & getrecommendations! Published in 2017 at "Hormones and Behavior"
DOI: 10.1016/j.yhbeh.2016.10.010
Abstract: &NA; Cognitive changes that occur during mid‐life and beyond are linked to both aging and the menopause transition. Studies in women suggest that the age at menopause onset can impact cognitive status later in life;… read more here.
Keywords: follicular depletion; age; menopause transition; menopause ... See more keywords