Hemagglutinin Functionalized Liposomal Vaccines Enhance Germinal Center and Follicular Helper T Cell Immunity
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202002142
Abstract: Abstract Despite remarkable successes of immunization in protecting public health, safe and effective vaccines against a number of life‐threatening pathogens such as HIV, ebola, influenza, and SARS‐CoV‐2 remain urgently needed. Subunit vaccines can avoid potential… read more here.
Keywords: cell; follicular helper; liposomal vaccines; helper cell ... See more keywords
Specific microbiota enhances intestinal IgA levels by inducing TGF‐β in T follicular helper cells of Peyer's patches in mice
Sign Up to like & getrecommendations! Published in 2020 at "European Journal of Immunology"
DOI: 10.1002/eji.201948474
Abstract: In humans and mice, mucosal immune responses are dominated by IgA antibodies and the cytokine TGF‐β, suppressing unwanted immune reactions but also targeting Ig class switching to IgA. It had been suggested that eosinophils promote… read more here.
Keywords: iga levels; intestinal iga; microbiota; iga ... See more keywords
Clonal composition and persistence of antigen‐specific circulating T follicular helper cells
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Immunology"
DOI: 10.1002/eji.202250190
Abstract: T follicular helper (TFH) cells play an essential role in promoting B cell responses and antibody affinity maturation in germinal centers (GC). A subset of memory CD4+ T cells expressing the chemokine receptor CXCR5 has… read more here.
Keywords: ctfh; ctfh cells; follicular helper; ctfh non ... See more keywords
Complete Visualization of T Follicular Helper Cells in Germinal Centers by Light Sheet Fluorescence Microscopy.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1736-6_1
Abstract: Long-lasting immunity depends on generation of antibody forming cells in germinal centers (GCs). Conventional methods such as immunohistology and intravital live imaging have been used extensively to investigate the location of cellular assemblies within tissues… read more here.
Keywords: microscopy; cells germinal; germinal centers; follicular helper ... See more keywords
Evaluation of Human Circulating T Follicular Helper Cells in Influenza- and SARS-CoV-2-Specific B Cell Immunity.
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DOI: 10.1007/978-1-0716-1736-6_17
Abstract: Generation of effective immune protection against viral infection and vaccination depends greatly on a successful engagement and stimulation of adaptive immune B cells and a specialized CD4+ T cell subset called T follicular helper cells… read more here.
Keywords: influenza sars; helper cells; follicular helper; sars cov ... See more keywords
T Follicular Helper Cells in Asthma Through Murine Models of Allergic Airway Disease.
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DOI: 10.1007/978-1-0716-1736-6_20
Abstract: The development of allergen-specific IgE is one of the hallmark symptoms of allergic diseases, including asthma. T follicular helper cells (TFH) are a subset of CD4+ T cells that play a critical role in T-dependent… read more here.
Keywords: allergic airway; airway disease; helper cells; follicular helper ... See more keywords
3D Tissue Explant and Single-Cell Suspension Organoid Culture Systems for Ex Vivo Drug Testing on Human Tonsil-Derived T Follicular Helper Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-1736-6_22
Abstract: Research on the human immune system is often restricted to peripheral blood cells. However, these cells can be different from those found in secondary lymphoid organs. For instance, specialized T and B cells that are… read more here.
Keywords: tissue; helper cells; follicular helper; culture ... See more keywords
Dysregulation of circulating follicular helper T cells in type 2 diabetic patients with diabetic retinopathy.
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DOI: 10.1007/s12026-021-09182-8
Abstract: Inflammation is known to be involved in the progression of diabetic retinopathy. Follicular helper T cells (Tfh) play critical roles in the differentiation of long-live plasma cells and production of antibodies, whereas circulating CD4+CXCR5+ T… read more here.
Keywords: circulating tfh; helper cells; follicular helper; diabetic retinopathy ... See more keywords
Galectin-9 regulates follicular helper T cells to inhibit humoral autoimmunity-induced pulmonary fibrosis.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.11.097
Abstract: Interstitial pneumonia with autoimmune features (IPAF) is an unexplained disease state characterized by autoimmunity and pulmonary fibrosis. Exploring the pathogenesis of IPAF is helpful for the treatment of interstitial pneumonia and idiopathic pulmonary fibrosis. In… read more here.
Keywords: fibrosis; helper cells; follicular helper; pulmonary fibrosis ... See more keywords
Context-Dependent Role for T-bet in T Follicular Helper Differentiation and Germinal Center Function following Viral Infection
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DOI: 10.1016/j.celrep.2019.07.034
Abstract: SUMMARY Following infection, inflammatory cues upregulate core transcriptional programs to establish pathogen-specific protection. In viral infections, T follicular helper (TFH) cells express the prototypical T helper 1 transcription factor T-bet. Several studies have demonstrated essential… read more here.
Keywords: role bet; infection; bet; follicular helper ... See more keywords
Characterization of follicular T helper cells and donor-specific T helper cells in renal transplant patients with de novo donor-specific HLA-antibodies.
Sign Up to like & getrecommendations! Published in 2021 at "Clinical immunology"
DOI: 10.1016/j.clim.2021.108698
Abstract: T follicular helper (TFH) cells are a heterogeneous subset of immunocompetent T helper (TH) cells capable of augmenting B cell responses in lymphoid tissues. In transplantation, exposure to allogeneic tissue activates TFH cells increasing the… read more here.
Keywords: specific hla; helper; follicular helper; helper cells ... See more keywords