Transcriptome Landscape of Human Folliculogenesis Reveals Oocyte and Granulosa Cell Interactions.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular cell"
DOI: 10.1016/j.molcel.2018.10.029
Abstract: The dynamic transcriptional regulation and interactions of human germlines and surrounding somatic cells during folliculogenesis remain unknown. Using RNA sequencing (RNA-seq) analysis of human oocytes and corresponding granulosa cells (GCs) spanning five follicular stages, we… read more here.
Keywords: transcriptome landscape; folliculogenesis reveals; human folliculogenesis; folliculogenesis ... See more keywords
Obesity alters ovarian folliculogenesis through disrupted angiogenesis from increased IL-10 production
Sign Up to like & getrecommendations! Published in 2021 at "Molecular Metabolism"
DOI: 10.1016/j.molmet.2021.101189
Abstract: Objective Obesity has been reported to have a modulatory effect on the ovulatory functions of patients with polycystic ovary syndrome. The role of adipokines in this obesity-associated ovulatory disturbance has not been extensively explored. In… read more here.
Keywords: ovarian folliculogenesis; increased production; folliculogenesis; model ... See more keywords
126 Subcortical maternal complex (SCMC) expression during folliculogenesis is affected by oocyte donor age in sheep
Sign Up to like & getrecommendations! Published in 2020 at "Reproduction, Fertility and Development"
DOI: 10.1071/rdv32n2ab126
Abstract: Age-associated decline in female fertility is largely attributable to decrease in oocyte quality. However, the molecular mechanisms that shape oocyte developmental competence, and that may be involved in reproductive aging, are yet to be elucidated.… read more here.
Keywords: age; scmc; oocyte; folliculogenesis ... See more keywords
Abnormal early folliculogenesis due to impeded pyruvate metabolism in mouse oocytes†
Sign Up to like & getrecommendations! Published in 2021 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioab064
Abstract: Abstract Fetal ovarian germ cells show characteristic energy metabolism status, such as enhanced mitochondrial metabolism as well as glycolysis, but their roles in early folliculogenesis are unclear. We show here that inhibition of pyruvate uptake… read more here.
Keywords: folliculogenesis; early folliculogenesis; pyruvate metabolism; abnormal early ... See more keywords
Recapitulating folliculogenesis and oogenesis outside the body: encapsulated in vitro follicle growth
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac176
Abstract: Abstract Folliculogenesis is a tightly coordinated process essential for generating a fertilization-competent gamete while also producing gonadal hormones that sustain endocrine function. In vitro follicle growth systems have been critical to our understanding of key… read more here.
Keywords: follicle growth; growth; vitro follicle; follicle ... See more keywords
Quantitative proteomic analysis uncovers protein-expression profiles during gonadotropin-dependent folliculogenesis in mice
Sign Up to like & getrecommendations! Published in 2022 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioac217
Abstract: Abstract Ovarian follicle is the basic functional unit of female reproduction, and is composed of oocyte and surrounding granulosa cells. In mammals, folliculogenesis strictly rely on gonadotropin regulations to determine the ovulation and the quality… read more here.
Keywords: gonadotropin dependent; quantitative proteomic; dependent folliculogenesis; expression ... See more keywords
P–458 A computational biology approach to improve in-vitro folliculogenesis
Sign Up to like & getrecommendations! Published in 2021 at "Human Reproduction"
DOI: 10.1093/humrep/deab130.457
Abstract: Considering the complexity of mechanisms involved in mammalian ovarian folliculogenesis, how about improving the current in-vitro folliculogenesis (ivF) protocols to prolong individual reproductive chance? Computational modelling approach based on network theory was used to manage… read more here.
Keywords: network; vitro folliculogenesis; folliculogenesis; ivf ... See more keywords
Biomechanical forces and signals operating in the ovary during folliculogenesis and their dysregulation: implications for fertility.
Sign Up to like & getrecommendations! Published in 2022 at "Human reproduction update"
DOI: 10.1093/humupd/dmac031
Abstract: BACKGROUND Folliculogenesis occurs in the highly dynamic environment of the ovary. Follicle cyclic recruitment, neo-angiogenesis, spatial displacement, follicle atresia and ovulation stand out as major events resulting from the interplay between mechanical forces and molecular… read more here.
Keywords: endometriosis; fertility; recruitment growth; dysregulation ... See more keywords
Assessment of folliculogenesis in ovarian tissue from young patients with Turner syndrome using a murine xenograft model.
Sign Up to like & getrecommendations! Published in 2023 at "Fertility and sterility"
DOI: 10.2139/ssrn.4290632
Abstract: OBJECTIVE To study the impact of aneuploid granulosa and stromal cells on folliculogenesis of small ovarian follicles from mosaic Turner syndrome patients using a murine xenograft model. DESIGN Laboratory study SUBJECTS: Ovarian cortical tissue was… read more here.
Keywords: turner syndrome; ovarian tissue; syndrome patients; folliculogenesis ... See more keywords
Disruption of Epidermal Growth Factor Receptor but Not EGF Blocks Follicle Activation in Zebrafish Ovary
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.750888
Abstract: Folliculogenesis is controlled by intimate communications between oocytes and surrounding follicle cells. Epidermal growth factor (EGF/Egf) is an important paracrine/autocrine factor in vertebrate ovary, and it is well known for its stimulation of oocyte maturation.… read more here.
Keywords: egf; follicle activation; growth; folliculogenesis ... See more keywords
Lipid Metabolic Process Involved in Oocyte Maturation During Folliculogenesis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.806890
Abstract: Oocyte maturation is a complex and dynamic process regulated by the coordination of ovarian cells and numerous extraovarian signals. From mammal studies, it is learnt that lipid metabolism provides sufficient energy for morphological and cellular… read more here.
Keywords: lipid metabolism; oocyte maturation; process; lipid metabolic ... See more keywords