Follistatin-controlled activin-HNF4α-coagulation factor axis in liver progenitor cells determines outcome of acute liver failure.
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.32119
Abstract: BACKGROUND & AIMS In patients with acute liver failure (ALF) who suffer from massive hepatocyte loss, liver progenitor cells (LPC) take over key hepatocyte functions, which ultimately determines survival. This study investigated how the expression… read more here.
Keywords: coagulation; liver failure; follistatin; hnf4 ... See more keywords
A novel role for follistatin in hypersensitivity following cystitis
Sign Up to like & getrecommendations! Published in 2017 at "Neurourology and Urodynamics"
DOI: 10.1002/nau.22941
Abstract: Previous studies have shown that the activin‐binding protein follistatin reduces inflammation in several mouse models of colitis. To determine whether follistatin also has a beneficial effect following bladder inflammation, we induced cystitis in mice using… read more here.
Keywords: cystitis; follistatin; novel role; role follistatin ... See more keywords
GW29-e1603 The effect of activin A-follistatin system imbalance on myocardial fibrosis of heart failure and the regulation of ghrelin
Sign Up to like & getrecommendations! Published in 2018 at "Journal of the American College of Cardiology"
DOI: 10.1016/j.jacc.2018.08.182
Abstract: Ghrelin, a novel growth hormone–releasing peptide, potentially improves cardiac function, but the mechanisms remain unclear. Activin A (Act A) is a member of the transforming growth factor beta (TGF-β) superfamily, which is closely associated with… read more here.
Keywords: fibrosis; follistatin; effect activin; gw29 e1603 ... See more keywords
Role of bone morphogenetic protein signaling in bovine early embryonic development and stage specific embryotropic actions of follistatin†
Sign Up to like & getrecommendations! Published in 2020 at "Biology of Reproduction"
DOI: 10.1093/biolre/ioz235
Abstract: Abstract Characterization of the molecular factors regulating early embryonic development and their functional mechanisms is critical for understanding the causes of early pregnancy loss in monotocous species (cattle, human). We previously characterized a stage specific… read more here.
Keywords: embryotropic actions; follistatin; embryonic development; stage specific ... See more keywords
AB0053 ACTIVIN A AND FOLLISTATIN AFFECT THE INTERACTION OF ENDOTHELIAL CELLS AND RHEUMATOID ARTHRITIS SYNOVIAL FIBROBLASTS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.4599
Abstract: Background: Activin A and its antagonist follistatin are part of an autoregulatory cycle, which is well known in the hypothalamic-pituitary-gonadal axis. Activins also have an important function in autoimmune diseases, such as rheumatoid arthritis (RA).… read more here.
Keywords: activin; follistatin; rasf; endothelial cells ... See more keywords
Follistatin forms a stable complex with Inhibin A that does not interfere with Activin A antagonism.
Sign Up to like & getrecommendations! Published in 2023 at "Endocrinology"
DOI: 10.1210/endocr/bqad017
Abstract: Inhibins are TGF-β family heterodimers that suppress follicle-stimulating hormone (FSH) secretion by antagonizing activin class ligands. Inhibins share a common β chain with activin ligands. Follistatin is another activin antagonist, known to bind the common… read more here.
Keywords: complex inhibin; follistatin; follistatin 288; activin antagonism ... See more keywords
Pre- and Peri-/Post-Compaction Follistatin Treatment Increases In Vitro Production of Cattle Embryos
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0170808
Abstract: Our previous studies demonstrated that maternal (oocyte derived) follistatin (FST) expression is positively associated with bovine oocyte competence and exogenous follistatin treatment during the pre-compaction period of development (d 1–3 post insemination) is stimulatory to… read more here.
Keywords: follistatin; follistatin treatment; compaction; post ... See more keywords
Follistatin attenuates radiation-induced fibrosis in a murine model
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DOI: 10.1371/journal.pone.0173788
Abstract: Purpose Fibrosis can be a disabling, severe side effect of radiotherapy that can occur in patients, and for which there is currently no effective treatment. The activins, proteins which are members of the TGFβ superfamily,… read more here.
Keywords: fibrosis; follistatin; radiation induced; murine model ... See more keywords
Activin/follistatin system in grass carp pituitary cells: - Regulation by local release of growth hormone and luteinizing hormone and its functional role in growth hormone synthesis and secretion
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0179789
Abstract: Gonadotrophin regulation by activin/follistatin system is well-documented, but the corresponding effect on growth hormone (GH) has not been fully characterized and with little information available in lower vertebrates, especially in fish models. In grass carp,… read more here.
Keywords: follistatin system; activin; follistatin; growth hormone ... See more keywords
Follistatin-like 1 and Biomarkers of Neutrophil Activation Are Associated with Poor Short-Term Outcome after Lung Transplantation on VA-ECMO
Sign Up to like & getrecommendations! Published in 2022 at "Biology"
DOI: 10.3390/biology11101475
Abstract: Simple Summary The determination of biomarkers linked to adverse outcome after lung transplantation is crucial to identify vulnerable recipients and to define targeted therapeutic options. In this study, we investigated the perioperative course of a… read more here.
Keywords: lung transplantation; outcome; follistatin like; follistatin ... See more keywords