Aqueous mediated iodine catalyzed C-N coupling followed by C-C coupling towards 5H-pyrazino[2,3-b]indoles.
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DOI: 10.1039/d3cc01631e
Abstract: Our study describes a new development featuring iodine-catalyzed two consecutive oxidative cross-coupling reactions involving Cα(sp3)-H of benzyl amines followed by intramolecular cyclization in water under air. Here, C-N coupling followed by C-C coupling occurs in… read more here.
Keywords: aqueous mediated; followed coupling; pyrazino indoles; coupling followed ... See more keywords