PD-1 blockade following ART interruption enhances control of pathogenic SIV in rhesus macaques
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2202148119
Abstract: Significance Anti-viral CD8 T cells express high levels of the co-inhibitory receptor programmed death-1 (PD-1) during chronic HIV and Simian immunodeficiency virus (SIV) infections and in vivo PD-1 blockade during chronic SIV infection restores CD8… read more here.
Keywords: control; blockade following; blockade; following art ... See more keywords
Risk of genetic and epigenetic alteration in children conceived following ART: Is it time to return to nature whenever possible?
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DOI: 10.1111/cge.14232
Abstract: Assisted reproductive technology may influence epigenetic signature as the procedures coincide with the extensive epigenetic modification occurring from fertilization to embryo implantation. However, it is still unclear to what extent ART alters the embryo epigenome.… read more here.
Keywords: epigenetic alteration; risk genetic; art; following art ... See more keywords