H3K4me3 recognition by the COMPASS complex facilitates the restoration of this histone mark following DNA replication
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abm6246
Abstract: During DNA replication, parental H3-H4 marked by H3K4me3 are transferred almost equally onto leading and lagging strands of DNA replication forks. Mutations in replicative helicase subunit, Mcm2 (Mcm2-3A), and leading strand DNA polymerase subunit, Dpb3… read more here.
Keywords: h3k4me3; restoration; dna; dna replication ... See more keywords
Direct binding of RNF8 to SUMO2/3 promotes cell survival following DNA damage.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular medicine reports"
DOI: 10.3892/mmr.2017.7624
Abstract: Ring finger protein 8 (RNF8), an FHA/RING domain containing E3 ubiquitin ligase, is critical in supporting genome integrity by facilitating the assembly of multiple DNA repair proteins at DNA lesions following DNA damage. In the… read more here.
Keywords: following dna; rnf8; dna damage; sumo2 ... See more keywords