Agonist immunotherapy restores T cell function following MEK inhibition improving efficacy in breast cancer
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/s41467-017-00728-9
Abstract: The presence of tumor-infiltrating lymphocytes in triple-negative breast cancers is correlated with improved outcomes. Ras/MAPK pathway activation is associated with significantly lower levels of tumor-infiltrating lymphocytes in triple-negative breast cancers and while MEK inhibition can… read more here.
Keywords: following mek; infiltrating lymphocytes; mek inhibition; inhibition ... See more keywords