Enhancing Base Excision Repair of Mitochondrial DNA to Reduce Ischemic Injury Following Reperfusion
Sign Up to like & getrecommendations! Published in 2018 at "Translational Stroke Research"
DOI: 10.1007/s12975-018-0680-5
Abstract: We hypothesize that enhancing mitochondrial base excision repair (BER) capability in brain will reduce reperfusion-associated ischemic brain injury. Post-stroke reperfusion was modeled in mice via transient filament occlusion of the middle cerebral artery (60 min) (transient… read more here.
Keywords: base excision; following reperfusion; excision repair; reperfusion ... See more keywords
Varenicline limits ischemia reperfusion injury following testicular torsion in mice.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of pediatric urology"
DOI: 10.1016/j.jpurol.2021.07.004
Abstract: BACKGROUND Torsion of the spermatic cord and the resulting testicular ischemia leads to the production of inflammatory cytokines and cell death due to impaired aerobic metabolism. Following reperfusion of the testis, a robust innate inflammatory… read more here.
Keywords: testicular torsion; torsion; following reperfusion; varenicline ... See more keywords