When Will Fondaparinux Induce Thrombocytopenia?
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DOI: 10.1021/acs.bioconjchem.2c00316
Abstract: The pentasaccharide Fondaparinux, a synthetic selective factor Xa inhibitor, is one of the safest anticoagulants in the heparin family that is recommended as an alternative drug for patients with hypersensitivity to other drugs such as… read more here.
Keywords: fondaparinux; microscopy; concentration; thrombocytopenia ... See more keywords
Fondaparinux in a critically Ill patient with heparin-induced thrombocytopenia
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DOI: 10.1097/md.0000000000012236
Abstract: Rationale: Fondaparinux, as a factor Xa-inhibitor, is used off label to manage heparin-induced thrombocytopenia (HIT), but little experience with HIT patients has been reported in the literature. Moreover, the use of fondaparinux for full anticoagulation… read more here.
Keywords: fondaparinux; heparin; ill patient; induced thrombocytopenia ... See more keywords
Fondaparinux pentasaccharide reduces sepsis coagulopathy and promotes survival in the baboon model of Escherichia coli sepsis
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DOI: 10.1111/jth.14642
Abstract: Sepsis triggers dysfunction of coagulation and fibrinolytic systems leading to disseminated intravascular coagulation (DIC) that contributes to organ failure and death. Fondaparinux (FPX) is a synthetic pentasaccharide that binds to antithrombin (AT) and selectively inhibits… read more here.
Keywords: sepsis; fondaparinux; pentasaccharide reduces; fondaparinux pentasaccharide ... See more keywords
Low-Molecular-Weight Heparin and Fondaparinux Use in Pediatric Patients With Obesity
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DOI: 10.1177/1060028020955029
Abstract: Objective: The objective of this study is to comprehensively review the efficacy and safety data of low-molecular-weight heparins (LMWHs) and fondaparinux in pediatric patients with obesity. Data Sources: A comprehensive literature search of PubMed, SCOPUS,… read more here.
Keywords: low molecular; fondaparinux; patients obesity; molecular weight ... See more keywords