Articles with "fondaparinux pentasaccharide" as a keyword



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Fondaparinux pentasaccharide reduces sepsis coagulopathy and promotes survival in the baboon model of Escherichia coli sepsis

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Published in 2019 at "Journal of Thrombosis and Haemostasis"

DOI: 10.1111/jth.14642

Abstract: Sepsis triggers dysfunction of coagulation and fibrinolytic systems leading to disseminated intravascular coagulation (DIC) that contributes to organ failure and death. Fondaparinux (FPX) is a synthetic pentasaccharide that binds to antithrombin (AT) and selectively inhibits… read more here.

Keywords: sepsis; fondaparinux; pentasaccharide reduces; fondaparinux pentasaccharide ... See more keywords