Structured illumination microscopy and automatized image processing as a rapid diagnostic tool for podocyte effacement
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DOI: 10.1038/s41598-017-11553-x
Abstract: The morphology of podocyte foot processes is obligatory for renal function. Here we describe a method for the superresolution-visualization of podocyte foot processes using structured illumination microscopy of the slit diaphragm, which before has only… read more here.
Keywords: microscopy; illumination microscopy; effacement; structured illumination ... See more keywords
PFKP Activation Ameliorates Foot Process Fusion in Podocytes in Diabetic Kidney Disease
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DOI: 10.3389/fendo.2021.797025
Abstract: Background Glycolysis dysfunction is an important pathogenesis of podocyte injury in diabetic kidney disease (DKD). Foot process fusion of podocytes and increased albuminuria are markers of early DKD. Moreover, cytoskeletal remodeling has been found to… read more here.
Keywords: fusion podocytes; cytoskeletal remodeling; foot process; process fusion ... See more keywords
Comparative Analysis of Podocyte Foot Process Morphology in Three Species by 3D Super-Resolution Microscopy
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2018.00292
Abstract: Since the size selectivity of the filtration barrier and kidney function are highly dependent on podocyte foot process morphology, visualization of foot processes is important. However, the size of foot processes is below the optical… read more here.
Keywords: foot process; process morphology; foot; microscopy ... See more keywords