A phase II trial of the effect of perindopril on hand–foot skin reaction (HFSR) incidence and severity in patients receiving regorafenib for refractory mCRC
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3738-x
Abstract: PurposeRegorafenib is an oral multi-kinase inhibitor that offers an OS benefit to patients with mCRC refractory to standard therapy (Grothey et al., in Lancet 381:303–312, 2013), but comes with potential significant toxicities including grade 3… read more here.
Keywords: foot skin; skin reaction; hfsr; severity ... See more keywords
Sorafenib-associated hand-foot skin reaction: practical advice on diagnosis, mechanism, prevention, and management
Sign Up to like & getrecommendations! Published in 2019 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2019.1689122
Abstract: ABSTRACT Introduction: Sorafenib is a multitargeted tyrosine kinase inhibitor, which has been mainly used in the treatment of advanced hepatocellular carcinoma and renal cancer. However, hand-foot skin reaction (HFSR), as one of the most common… read more here.
Keywords: foot skin; mechanism; hfsr; sorafenib ... See more keywords
Dramatic improvement of lenvatinib‐induced hand‐foot skin reaction with 7‐day oral prednisolone and acitretin
Sign Up to like & getrecommendations! Published in 2022 at "Australasian Journal of Dermatology"
DOI: 10.1111/ajd.13815
Abstract: A 60-year-old man of hepatocellular carcinoma with distant metastasis underwent target therapy with lenvatinib for cancer management. Three weeks later, numerous dark violaceous to deep brownish, painful, and hyperkeratotic plaques with peeling were noted over… read more here.
Keywords: hand foot; oral prednisolone; prednisolone acitretin; foot skin ... See more keywords
Topical sildenafil in the treatment of hand-foot syndrome and hand-foot skin reaction: A retrospective study.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e22095
Abstract: e22095Background: Hand-foot syndrome (HFS) and hand-foot skin reaction (HFSR) are painful, debilitating, and often dose-limiting complications of anticancer agents. These cutaneous reactions are en... read more here.
Keywords: foot skin; foot syndrome; skin reaction; hand ... See more keywords
A case report for severe hand-foot skin reaction caused by chemotherapy with actinomycin D in a patient with oculocutaneous albinism
Sign Up to like & getrecommendations! Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s195635
Abstract: Gestational trophoblastic neoplasms (GTN) are highly curable tumors, with an overall patient survival of 90%, due to the individualized chemotherapy. However, chemotherapy regimens vary between different treatment centers and the comparable benefits and risks of… read more here.
Keywords: severe hand; oculocutaneous albinism; foot skin; drug ... See more keywords
Challenge of Bovine Foot Skin Fibroblasts With Digital Dermatitis Treponemes Identifies Distinct Pathogenic Mechanisms
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.538591
Abstract: Bovine digital dermatitis (BDD) is a common infectious disease of digital skin in cattle and an important cause of lameness worldwide, with limited treatment options. It is of increasing global concern for both animal welfare… read more here.
Keywords: bdd treponemes; foot skin; pathogenic mechanisms; skin ... See more keywords
Factors Influencing Microbiological Biodiversity of Human Foot Skin
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DOI: 10.3390/ijerph16183503
Abstract: The aim of the study was to analyze the microbiological biodiversity of human foot skin with respect to factors such as age, gender, frequency of foot washing and physical activity, and to select indicator species… read more here.
Keywords: foot skin; biodiversity human; microbiological biodiversity; number ... See more keywords
Influence of Upper Footwear Material Properties on Foot Skin Temperature, Humidity and Perceived Comfort of Older Individuals
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DOI: 10.3390/ijerph191710861
Abstract: Studying the in-shoe microclimate of older individuals is important for enhancing their foot comfort and preventing foot diseases. However, there is a lack of scientific work that explores the thermo-physiological wear comfort of older individuals… read more here.
Keywords: skin temperature; foot skin; comfort; older individuals ... See more keywords
Sorafenib-induced grade III hand–foot skin reaction with ulcerative dermatitis on scrotum, penis, and earlobe
Sign Up to like & getrecommendations! Published in 2019 at "Indian Journal of Dermatology, Venereology and Leprology"
DOI: 10.4103/ijdvl.ijdvl_67_19
Abstract: Sir, A 60‐year‐old male with grade III hepatocellular carcinoma taking sorafenib 400 mg twice daily since 10 days was referred to the dermatology outpatient department for erosions and ulcerations on scrotum, penis, and frictional zones… read more here.
Keywords: foot skin; scrotum penis; grade iii; dermatology ... See more keywords