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Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3738-x
Abstract: PurposeRegorafenib is an oral multi-kinase inhibitor that offers an OS benefit to patients with mCRC refractory to standard therapy (Grothey et al., in Lancet 381:303–312, 2013), but comes with potential significant toxicities including grade 3…
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Keywords:
foot skin;
skin reaction;
hfsr;
severity ... See more keywords
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Published in 2019 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2019.1689122
Abstract: ABSTRACT Introduction: Sorafenib is a multitargeted tyrosine kinase inhibitor, which has been mainly used in the treatment of advanced hepatocellular carcinoma and renal cancer. However, hand-foot skin reaction (HFSR), as one of the most common…
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Keywords:
foot skin;
mechanism;
hfsr;
sorafenib ... See more keywords
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1
Published in 2022 at "Australasian Journal of Dermatology"
DOI: 10.1111/ajd.13815
Abstract: A 60-year-old man of hepatocellular carcinoma with distant metastasis underwent target therapy with lenvatinib for cancer management. Three weeks later, numerous dark violaceous to deep brownish, painful, and hyperkeratotic plaques with peeling were noted over…
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Keywords:
hand foot;
oral prednisolone;
prednisolone acitretin;
foot skin ... See more keywords
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1
Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.15_suppl.e22095
Abstract: e22095Background: Hand-foot syndrome (HFS) and hand-foot skin reaction (HFSR) are painful, debilitating, and often dose-limiting complications of anticancer agents. These cutaneous reactions are en...
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Keywords:
foot skin;
foot syndrome;
skin reaction;
hand ... See more keywords
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Published in 2019 at "OncoTargets and therapy"
DOI: 10.2147/ott.s195635
Abstract: Gestational trophoblastic neoplasms (GTN) are highly curable tumors, with an overall patient survival of 90%, due to the individualized chemotherapy. However, chemotherapy regimens vary between different treatment centers and the comparable benefits and risks of…
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Keywords:
severe hand;
oculocutaneous albinism;
foot skin;
drug ... See more keywords
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Published in 2020 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2020.538591
Abstract: Bovine digital dermatitis (BDD) is a common infectious disease of digital skin in cattle and an important cause of lameness worldwide, with limited treatment options. It is of increasing global concern for both animal welfare…
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Keywords:
bdd treponemes;
foot skin;
pathogenic mechanisms;
skin ... See more keywords
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Published in 2019 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph16183503
Abstract: The aim of the study was to analyze the microbiological biodiversity of human foot skin with respect to factors such as age, gender, frequency of foot washing and physical activity, and to select indicator species…
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Keywords:
foot skin;
biodiversity human;
microbiological biodiversity;
number ... See more keywords
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1
Published in 2022 at "International Journal of Environmental Research and Public Health"
DOI: 10.3390/ijerph191710861
Abstract: Studying the in-shoe microclimate of older individuals is important for enhancing their foot comfort and preventing foot diseases. However, there is a lack of scientific work that explores the thermo-physiological wear comfort of older individuals…
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Keywords:
skin temperature;
foot skin;
comfort;
older individuals ... See more keywords
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Published in 2019 at "Indian Journal of Dermatology, Venereology and Leprology"
DOI: 10.4103/ijdvl.ijdvl_67_19
Abstract: Sir, A 60‐year‐old male with grade III hepatocellular carcinoma taking sorafenib 400 mg twice daily since 10 days was referred to the dermatology outpatient department for erosions and ulcerations on scrotum, penis, and frictional zones…
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Keywords:
foot skin;
scrotum penis;
grade iii;
dermatology ... See more keywords