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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2202269119
Abstract: Significance The mechanosensitive ion channel Piezo1 plays many important physiological functions. This essential ion channel is selectively activated by a synthetic small molecule called Yoda1. Despite current efforts to develop Yoda1 analogs with potential clinical…
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Keywords:
temperature;
footprint piezo1;
piezo1 channels;
energetic footprint ... See more keywords