Automated Specific Amino Acid Footprinting Mass Spectrometry: Repurposing an HDX Platform for Determining Reagent Feasibility.
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DOI: 10.1021/acs.analchem.2c02073
Abstract: Protein footprinting is a mass spectrometry (MS)-based approach to measure protein conformational changes. One approach, specific amino acid labeling, imparts often an irreversible modification to protein side chains but requires careful selection of the reactive… read more here.
Keywords: mass spectrometry; footprinting mass; amino acid; specific amino ... See more keywords