Force-dependent stimulation of RNA unwinding by SARS-CoV-2 nsp13 helicase
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2020.11.2276
Abstract: The superfamily 1 helicase nonstructural protein 13 (nsp13) is required for SARS-CoV-2 replication. The mechanism and regulation of nsp13 has not been explored at the single-molecule level. Specifically, force-dependent unwinding experiments have yet to be… read more here.
Keywords: dependent stimulation; rna; helicase; sars cov ... See more keywords
Force-dependent induced transparency in an atom-assisted optomechanical system
Sign Up to like & getrecommendations! Published in 2019 at "Optics Communications"
DOI: 10.1016/j.optcom.2018.12.068
Abstract: Abstract We theoretically investigate force-dependent induced transparency effect of an output field in an atom-assisted optomechanical system where a mechanical resonator is driven by a time-dependent force. It is shown that there exists an additional… read more here.
Keywords: induced transparency; dependent induced; force dependent; atom assisted ... See more keywords
Force-Dependent Interactions between Talin and Full-Length Vinculin.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.1c06223
Abstract: Talin and vinculin are part of a multicomponent system involved in mechanosensing in cell-matrix adhesions. Both exist in autoinhibited forms, and activation of vinculin requires binding to mechanically activated talin, yet how forces affect talin's… read more here.
Keywords: vinculin; force; dependent interactions; interactions talin ... See more keywords
Calculating the force-dependent unbinding rate of biological macromolecular bonds from force-ramp optical trapping assays
Sign Up to like & getrecommendations! Published in 2022 at "Scientific Reports"
DOI: 10.1038/s41598-021-03690-1
Abstract: The non-covalent biological bonds that constitute protein–protein or protein–ligand interactions play crucial roles in many cellular functions, including mitosis, motility, and cell–cell adhesion. The effect of external force ( $$F$$ F ) on the unbinding… read more here.
Keywords: dissociation; unbinding rate; spectroscopy; force ... See more keywords
Force-dependent elasticity of nucleic acids.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d2nr06324g
Abstract: The functioning of double-stranded (ds) nucleic acids (NAs) in cellular processes is strongly mediated by their elastic response. These processes involve proteins that interact with dsDNA or dsRNA and distort their structures. The perturbation of… read more here.
Keywords: force dependent; elasticity; elasticity nucleic; dsrna ... See more keywords
Introduction to Force-Dependent Kinematics: Theory and Application to Mandible Modeling.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4037100
Abstract: Knowledge of the muscle, ligament, and joint forces is important when planning orthopedic surgeries. Since these quantities cannot be measured in vivo under normal circumstances, the best alternative is to estimate them using musculoskeletal models.… read more here.
Keywords: kinematics; model; dependent kinematics; force dependent ... See more keywords