Building a dendritic actin filament network branch by branch: models of filament orientation pattern and force generation in lamellipodia
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical Reviews"
DOI: 10.1007/s12551-018-0475-7
Abstract: We review mathematical and computational models of the structure, dynamics, and force generation properties of dendritic actin networks. These models have been motivated by the dendritic nucleation model, which provided a mechanistic picture of how… read more here.
Keywords: network; actin; force generation; branch ... See more keywords
Balance between Force Generation and Relaxation Leads to Pulsed Contraction of Actomyosin Networks.
Sign Up to like & getrecommendations! Published in 2018 at "Biophysical journal"
DOI: 10.1016/j.bpj.2018.10.008
Abstract: Actomyosin contractility regulates various biological processes, including cell migration and cytokinesis. The cell cortex underlying the membrane of eukaryote cells exhibits dynamic contractile behaviors facilitated by actomyosin contractility. Interestingly, the cell cortex shows reversible aggregation… read more here.
Keywords: force generation; actomyosin; contraction; pulsed contraction ... See more keywords
The effect of handrail cross-sectional design and age on applied handrail forces during reach-to-grasp balance reactions.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of biomechanics"
DOI: 10.1016/j.jbiomech.2021.110788
Abstract: Handrails have been shown to reduce the likelihood of falls. Despite common use, little is known about how handrail shape and size affect the forces that people can apply after balance loss, and how these… read more here.
Keywords: handrail; force generation; handrail cross; balance ... See more keywords
The force generation mechanism of lifting surfaces with flow separation
Sign Up to like & getrecommendations! Published in 2021 at "Ocean Engineering"
DOI: 10.1016/j.oceaneng.2021.109749
Abstract: Abstract Fins, wings, blades and sails can generate lift and drag in both attached and separated flow conditions. However, the common understanding of the lift generation mechanism holds only for attached flow conditions. In fact,… read more here.
Keywords: generation; generation mechanism; flow separation; force generation ... See more keywords
Coordinated force generation of skeletal myosins in myofilaments through motor coupling
Sign Up to like & getrecommendations! Published in 2017 at "Nature Communications"
DOI: 10.1038/ncomms16036
Abstract: In contrast to processive molecular motors, skeletal myosins form a large motor ensemble for contraction of muscles against high loads. Despite numerous information on the molecular properties of skeletal myosin, its ensemble effects on collective… read more here.
Keywords: coordinated force; force generation; force; motor ... See more keywords
Elastomeric sensor surfaces for high-throughput single-cell force cytometry
Sign Up to like & getrecommendations! Published in 2018 at "Nature Biomedical Engineering"
DOI: 10.1038/s41551-018-0193-2
Abstract: As cells with aberrant force-generating phenotypes can directly lead to disease, cellular force-generation mechanisms are high-value targets for new therapies. Here, we show that single-cell force sensors embedded in elastomers enable single-cell force measurements with… read more here.
Keywords: single cell; force generation; force; cell force ... See more keywords
Active particles under confinement and effective force generation among surfaces.
Sign Up to like & getrecommendations! Published in 2018 at "Soft matter"
DOI: 10.1039/c8sm01840e
Abstract: We consider the effect of geometric confinement on the steady-state properties of a one-dimensional active suspension subject to thermal noise. The random active force is modeled by an Ornstein-Uhlenbeck process and the system is studied… read more here.
Keywords: active particles; effective force; force generation; confinement effective ... See more keywords
Direct measurement of cortical force generation and polarization in a living parasite
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e16-07-0518
Abstract: A laser trap was used to measure the molecular-scale forces generated at the surface of living Toxoplasma gondii in order to test the dominant theory of how these parasites move and invade host cells. The… read more here.
Keywords: direct measurement; measurement cortical; cortical force; force generation ... See more keywords
Force Generation in Confined Active Fluids: The Role of Microstructure.
Sign Up to like & getrecommendations! Published in 2022 at "Physical review letters"
DOI: 10.1103/physrevlett.129.058001
Abstract: We experimentally determine the force exerted by a bath of active particles onto a passive probe as a function of its distance to a wall and compare it to the measured averaged density distribution of… read more here.
Keywords: active particles; confined active; force generation; active fluids ... See more keywords
An EMG-Based Constitutive Law for Force Generation in Skeletal Muscle - Part I: Model Development.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of biomechanical engineering"
DOI: 10.1115/1.4053568
Abstract: PURPOSE This paper proposes a new method for estimating skeletal muscle forces using a model derived from dimensional analysis. It incorporates electromyography signals and muscle force-length, force-velocity, and force frequency relationships as inputs. The purpose… read more here.
Keywords: force generation; muscle; model; force ... See more keywords
A function of profilin in force generation during malaria parasite motility independent of actin binding.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of cell science"
DOI: 10.1242/jcs.233775
Abstract: During transmission of malaria-causing parasites from mosquito to mammal, Plasmodium sporozoites migrate at high speed within the skin to access the bloodstream and infect the liver. This unusual gliding motility is based on retrograde flow… read more here.
Keywords: profilin; force generation; actin binding; force ... See more keywords