Hexameric NuMA:LGN structures promote multivalent interactions required for planar epithelial divisions
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DOI: 10.1038/s41467-019-09999-w
Abstract: Cortical force generators connect epithelial polarity sites with astral microtubules, allowing dynein movement to orient the mitotic spindle as astral microtubules depolymerize. Complexes of the LGN and NuMA proteins, fundamental components of force generators, are… read more here.
Keywords: dynein dynactin; numa lgn; cortical force; lgn ... See more keywords