Aligned forces: Origins and mechanisms of cancer dissemination guided by extracellular matrix architecture.
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DOI: 10.1016/j.ceb.2021.05.004
Abstract: Organized extracellular matrix (ECM), in the form of aligned architectures, is a critical mediator of directed cancer cell migration by contact guidance, leading to metastasis in solid tumors. Current models suggest anisotropic force generation through… read more here.
Keywords: forces origins; extracellular matrix; matrix; aligned forces ... See more keywords
Driving forces in the origins of life
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DOI: 10.1098/rsob.200324
Abstract: What were the physico-chemical forces that drove the origins of life? We discuss four major prebiotic ‘discoveries’: persistent sampling of chemical reaction space; sequence-encodable foldable catalysts; assembly of functional pathways; and encapsulation and heritability. We… read more here.
Keywords: forces origins; driving forces; origins life; biology ... See more keywords