Forkhead box L2 is a target of miR‐133b and plays an important role in the pathogenesis of non‐small cell lung cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Medicine"
DOI: 10.1002/cam4.5746
Abstract: Forkhead box L2 (FOXL2) has been recognized as a transcription factor in the progression of many malignancies, but its role in non‐small cell lung cancer (NSCLC) remains unclear. This research clarified on the role of… read more here.
Keywords: forkhead box; non small; role; small cell ... See more keywords
Reciprocal Regulation Between Forkhead Box M1/NF‐κB and Methionine Adenosyltransferase 1A Drives Liver Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Hepatology"
DOI: 10.1002/hep.31196
Abstract: Forkhead box M1 (FOXM1) and nuclear factor kappa B (NF‐ĸB) are oncogenic drivers in liver cancer that positively regulate each other. We showed that methionine adenosyltransferase 1A (MAT1A) is a tumor suppressor in the liver… read more here.
Keywords: cancer; forkhead box; liver cancer; methionine adenosyltransferase ... See more keywords
Mechanical stress‐caused chondrocyte dysfunction and cartilage injury can be attenuated by dioscin via activating sirtuin1/forkhead box O1
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biochemical and Molecular Toxicology"
DOI: 10.1002/jbt.23212
Abstract: Sirtuin1 (Sirt1)/forkhead box O1 (FoxO1) axis has been reported as a crucial regulator involved in chondral homeostasis of healthy or osteoarthritis (OA) cartilage. In our study, the aim is to investigate whether dioscin functions as… read more here.
Keywords: forkhead box; mechanical stress; cartilage; chondrocyte dysfunction ... See more keywords
MiR‐216b inhibits osteosarcoma cell proliferation, migration, and invasion by targeting Forkhead Box M1
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27822
Abstract: Osteosarcoma (OS) is considered the most common type of primary malignant bone tumor, which has a high rate of mortality in children and adolescents. However, the current treatment methods for OS are ineffective. Therefore, there… read more here.
Keywords: 216b foxm1; mir 216b; forkhead box; invasion ... See more keywords
Forkhead box O4 transcription factor in human neoplasms: Cannot afford to lose the novel suppressor
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27853
Abstract: Forkhead box O4 (FOXO4), a member of FOXO family, has been highlighted as an essential transcriptional regulator in many diverse carcinomas. Accumulated studies have demonstrated that FOXO4 is downregulated and associated with tumorigenesis, invasiveness, and… read more here.
Keywords: box transcription; forkhead box; forkhead; transcription factor ... See more keywords
Forkhead Box Q1 is a novel regulator of autophagy in breast cancer cells.
Sign Up to like & getrecommendations! Published in 2023 at "Molecular carcinogenesis"
DOI: 10.1002/mc.23588
Abstract: Forkhead Box Q1 (FoxQ1) transcription factor is overexpressed in luminal-type and basal-type human breast cancers when compared to normal mammary tissue. This transcription factor is best known for its role in promotion of breast cancer… read more here.
Keywords: forkhead box; sum159; breast; breast cancer ... See more keywords
Forkhead box M1 transcription factor: a novel target for pulmonary arterial hypertension therapy
Sign Up to like & getrecommendations! Published in 2019 at "World Journal of Pediatrics"
DOI: 10.1007/s12519-019-00271-1
Abstract: Background Forkhead box M1 (FoxM1), a member of forkhead family, plays a key role in carcinogenesis, progression, invasion, metastasis and drug resistance. Based on the similarities between cancer and pulmonary arterial hypertension, studies on the… read more here.
Keywords: arterial hypertension; forkhead box; pulmonary arterial; foxm1 pulmonary ... See more keywords
Forkhead box-P3+ regulatory T cells and toll-like receptor 2 co-expression in oral squamous cell carcinoma.
Sign Up to like & getrecommendations! Published in 2017 at "Acta histochemica"
DOI: 10.1016/j.acthis.2016.12.005
Abstract: BACKGROUND The function of forkhead box-P3 (FoxP3) regulatory T cells (Treg) and toll-like receptor (TLR)2 protein in the oral cancer microenvironment is not fully understood, but evidence from other malignancies suggests it is likely they… read more here.
Keywords: toll like; tlr2; forkhead box; regulatory cells ... See more keywords
Novel role of forkhead box O 4 transcription factor in cancer: Bringing out the good or the bad.
Sign Up to like & getrecommendations! Published in 2018 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2018.04.007
Abstract: Forkhead box O (FOXO) family has recently been highlighted as important transcriptional regulators associated with many diverse carcinomas. Although redundant functionality between FOXO family members with cancer is known, regulatory ability of FOXO4 for tumorigenesis… read more here.
Keywords: cancer; factor; forkhead box; novel role ... See more keywords
Structure of a 14-3-3ε:FOXO3apS253 Phosphopeptide Complex Reveals 14-3-3 Isoform-Specific Binding of Forkhead Box Class O Transcription Factor (FOXO) Phosphoproteins
Sign Up to like & getrecommendations! Published in 2022 at "ACS Omega"
DOI: 10.1021/acsomega.2c01700
Abstract: The transcriptional activity of Forkhead Box O3 (FOXO3a) is inactivated by AKT-mediated phosphorylation on Serine 253 (S253), which enables FOXO3a binding to 14-3-3. Phosphorylated FOXO3a binding to 14-3-3 facilitates the nuclear exclusion of FOXO3a, causing… read more here.
Keywords: forkhead box; structure foxo3aps253; structure; foxo3aps253 phosphopeptide ... See more keywords
Forkhead Box 1(FoxO1) mediates psychological stress-induced neuroinflammation
Sign Up to like & getrecommendations! Published in 2022 at "Neurological Research"
DOI: 10.1080/01616412.2021.2022913
Abstract: ABSTRACT Objectives Neuroinflammation plays a key role in cerebrovascular disease (CVD). Neuropsychiatric disorders appear to share an epidemiological association with inflammation, but the mechanisms are unclear. Forkhead box 1 (FoxO1) regulates inflammatory signaling in diabetes… read more here.
Keywords: stress; forkhead box; induced neuroinflammation; stress induced ... See more keywords