Solubility measurement and thermodynamic modeling of carbamazepine (form III) in five pure solvents at various temperatures
Sign Up to like & getrecommendations! Published in 2020 at "Chinese Journal of Chemical Engineering"
DOI: 10.1016/j.cjche.2020.09.054
Abstract: Abstract In this work, the solubilities of carbamazepine (CBZ) (form III) in ethyl acetate, methyl acetate, ethylene glycol, chloroform and cyclohexylamine were determined by laser monitoring techniques at pressure above sea level, and the solubility… read more here.
Keywords: form iii; pure solvents; cbz form; form ... See more keywords
Crystal anisotropy explains structure‐mechanics impact on tableting performance of flufenamic acid polymorphs
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutics and Biopharmaceutics"
DOI: 10.1016/j.ejpb.2018.09.006
Abstract: Graphical abstract Figure. No Caption available. Abstract Anisotropic features with other crystallographic properties like d‐spacing, and attachment energy (Eatt) can predict material performance during the secondary pharmaceutical processing. A newly developed state‐of‐the‐art compression cell lodged… read more here.
Keywords: form iii; form; tableting performance; performance ... See more keywords
Understanding the Metastability of Theophylline FIII by Means of Low-Frequency Vibrational Spectroscopy.
Sign Up to like & getrecommendations! Published in 2021 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00476
Abstract: While theophylline has been extensively studied with multiple polymorphs discovered, there is still currently no conclusive structure for the metastable theophylline form III. In this present work, by combining more widely used techniques such as… read more here.
Keywords: form iii; theophylline; spectroscopy; structure ... See more keywords
Controlling crystal polymorphism of isotactic poly(1-butene) by incorporating long chain branches.
Sign Up to like & getrecommendations! Published in 2018 at "Soft matter"
DOI: 10.1039/c8sm01793j
Abstract: Isotactic poly(1-butene) (iPB-1) is a high performance plastic with outstanding properties, such as flexibility, superior creep, environmental stress cracking and abrasive resistance. However, it exhibits a complex crystal polymorphism and polymorphic transformation behavior, which has… read more here.
Keywords: isotactic poly; form iii; crystal polymorphism; long chain ... See more keywords
Probing anisotropic mechanical behaviour in carbamazepine form III
Sign Up to like & getrecommendations! Published in 2021 at "CrystEngComm"
DOI: 10.1039/d0ce01659d
Abstract: Nanoindentation measurements of the mechanical properties of the (020), (002) and (101) crystal faces in carbamazepine (CBZ) form III revealed that the (020) face had a greater elastic modulus and hardness than the (002) and… read more here.
Keywords: form; slip plane; form iii; 002 101 ... See more keywords
Polymorphs and hydrates of the anticancer drug erlotinib: X-ray crystallography, phase transition and biopharmaceutical studies
Sign Up to like & getrecommendations! Published in 2021 at "CrystEngComm"
DOI: 10.1039/d1ce00032b
Abstract: Erlotinib, a non-small cell lung cancer BCS class II drug, was found to occur as two polymorphs and two hydrates depending on the crystallization conditions. The monohydrate (form III), which has been reported in patents… read more here.
Keywords: form; polar solvents; form iii; erlotinib ... See more keywords
Impact of Solvent-Mediated Phase Transitions by Artificial Gastrointestinal Buffers on Efavirenz Polymorphs
Sign Up to like & getrecommendations! Published in 2025 at "Crystals"
DOI: 10.3390/cryst15010048
Abstract: The implications of various pH solutions in the gastrointestinal fluid system as solvent-mediated phase transitions on concurrent polymorphism transformation, notably metastable polymorphic forms of Efavirenz (EFV), has never been investigated. The impact will be shifting… read more here.
Keywords: phase transitions; solvent mediated; impact; form iii ... See more keywords