Chemical Decrosslinking-Based Peptide Characterization of Formaldehyde-Fixed Rat Pancreas Using Fluorescence-Guided Single-Cell Mass Spectrometry.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.3c00612
Abstract: Approaches for the characterization of proteins/peptides in single cells of formaldehyde-fixed (FF) tissues via mass spectrometry (MS) are still under development. The lack of a general method for selectively eliminating formaldehyde-induced crosslinking is a major… read more here.
Keywords: cell; mass spectrometry; formaldehyde fixed; fluorescence guided ... See more keywords
2086-P: Peptidyl Hormone Detection in Formaldehyde-Fixed Pancreas Using Mass Spectrometry Imaging
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes"
DOI: 10.2337/db20-2086-p
Abstract: The availability of well-documented high-quality clinical pancreas specimens in tissue depositories such as the nPOD allows multiplatform comparative investigations of the biochemical correlates of T1D and T2D disease progression. Mass spectrometry imaging (MSI) is an… read more here.
Keywords: detection; mass spectrometry; formaldehyde fixed; spectrometry imaging ... See more keywords