Pramipexole inhibits formalin‐induce acute and long‐lasting mechanical hypersensitivity via NF‐kB pathway in rats
Sign Up to like & getrecommendations! Published in 2023 at "Drug Development Research"
DOI: 10.1002/ddr.22029
Abstract: Pain is one of the most frequent causes for patients to seek medical care. It interferes with daily functioning and affects the quality of life of the patient. There is a clear need to investigate… read more here.
Keywords: acute long; ppx; long lasting; mechanical allodynia ... See more keywords
Formalin-induced inflammatory pain increases excitability in locus coeruleus neurons
Sign Up to like & getrecommendations! Published in 2021 at "Brain Research Bulletin"
DOI: 10.1016/j.brainresbull.2021.04.002
Abstract: Chronic pain is recognized as an important problem in communities. The Locus coeruleus (LC) with extensive ascending and descending projections has a critical role in modulating pain. Some studies indicate how the locus coeruleus-noradrenaline system… read more here.
Keywords: neurons formalin; inflammatory pain; locus coeruleus; formalin induced ... See more keywords
Possible involvement of the μ opioid receptor in the antinociception induced by sinomenine on formalin-induced nociceptive behavior in mice
Sign Up to like & getrecommendations! Published in 2019 at "Neuroscience Letters"
DOI: 10.1016/j.neulet.2019.01.035
Abstract: Sinomenine, an alkaloid originally isolated from the roots and the rhizome of Sinomenium acutum is used as a traditional Chinese herbal medicines for rheumatoid arthritis and neuralgia. The aims of this study were to investigate… read more here.
Keywords: receptor; opioid receptor; formalin induced; sinomenine ... See more keywords
Enhanced Activities of δ Subunit-containing GABAA Receptors Blocked Spinal Long-term Potentiation and Attenuated Formalin-induced Spontaneous Pain
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DOI: 10.1016/j.neuroscience.2017.12.002
Abstract: The δ subunit-containing γ-Aminobutyric acid type A receptors (δ-GABAARs) are located at extrasynaptic sites and persistently active in the control of neuronal excitability. Here we recorded primary afferent C fiber-evoked field potentials in the superficial… read more here.
Keywords: term potentiation; formalin; thip; subunit containing ... See more keywords
Antinociceptive effect of chrysin in diabetic neuropathy and formalin-induced pain models
Sign Up to like & getrecommendations! Published in 2020 at "Animal Cells and Systems"
DOI: 10.1080/19768354.2020.1765019
Abstract: ABSTRACT Chrysin, a natural flavonoid, is the main ingredient of many medicinal plants, which shows potent pharmacological properties. In the present study, the antinociceptive effects of chrysin were examined in ICR mice. Chrysin orally administered… read more here.
Keywords: diabetic neuropathy; chrysin; formalin induced; induced pain ... See more keywords
Deletion of MyD88 adaptor in nociceptor alleviates low-dose formalin-induced acute pain and persistent pain in mice
Sign Up to like & getrecommendations! Published in 2021 at "NeuroReport"
DOI: 10.1097/wnr.0000000000001608
Abstract: The myeloid differentiation factor 88 (MyD88) adaptor mediates signaling by Toll-like receptors and some interleukins (ILs) in neural and non-neuronal cells. Recently, MyD88 protein was found to express in primary sensory neurons and be involved… read more here.
Keywords: deletion; mice; pain; persistent pain ... See more keywords
Analgesic Effects of Duloxetine on Formalin-Induced Hyperalgesia and Its Underlying Mechanisms in the CeA
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2018.00317
Abstract: In rodents, the amygdala has been proposed to serve as a key center for the nociceptive perception. Previous studies have shown that extracellular signal-regulated kinase (ERK) signaling cascade in the central nucleus of amygdala (CeA)… read more here.
Keywords: cea; dul; formalin induced; analgesic effects ... See more keywords
Formalin induced Corrosive Mucosal Injury: A Rare Case Report
Sign Up to like & getrecommendations! Published in 2020 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2020.00052.9
Abstract: Formalin is an aqueous solution of formaldehyde (37%), which is a pungent and highly reactive gas. Ingestion of formalin is infrequent due to its strong odour and irritant effects. Here, we report a case of… read more here.
Keywords: formalin; case; report; formalin induced ... See more keywords