The Role of Formamidine Groups in Dextran Based Nonviral Vectors for Gene Delivery on Their Physicochemical and Biological Characteristics.
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202000220
Abstract: Dextran-formamidine esters (dextran-N-[(dimethylamino)methylene]-β-alanine ester) with different degrees of substitution (0.45-0.92) are synthesized in an one-pot reaction. Dextran (Mw 60 000 g mol-1 ) is allowed to react with unprotected beta-alanine and iminium chloride and investigated regarding… read more here.
Keywords: gene delivery; role; formamidine groups; gene ... See more keywords
Formamidine-based thiuram disulfides: Synthesis, structural characterization, biological studies, and preliminary cheminformatics evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2020.128553
Abstract: Abstract In this study, we present the synthesis and biological evaluation of a series of formamidine-based thiuram disulfides using computational tools. Six compounds were synthesized via, the oxidation of formamidine-based dithiocarbamates. These were, N,N′-bis(2,6-dimethylphenyl)formamidine dithiocarbamate… read more here.
Keywords: formamidine dithiocarbamate; dithiocarbamate; based thiuram; formamidine based ... See more keywords