The Role of Formamidine Groups in Dextran Based Nonviral Vectors for Gene Delivery on Their Physicochemical and Biological Characteristics.
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DOI: 10.1002/mabi.202000220
Abstract: Dextran-formamidine esters (dextran-N-[(dimethylamino)methylene]-β-alanine ester) with different degrees of substitution (0.45-0.92) are synthesized in an one-pot reaction. Dextran (Mw 60 000 g mol-1 ) is allowed to react with unprotected beta-alanine and iminium chloride and investigated regarding… read more here.
Keywords: gene delivery; role; formamidine groups; gene ... See more keywords