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Formation of Foamy Macrophages by Tuberculous Pleural Effusions Is Triggered by the Interleukin-10/Signal Transducer and Activator of Transcription 3 Axis through ACAT Upregulation

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Published in 2018 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2018.00459

Abstract: The ability of Mycobacterium tuberculosis (Mtb) to persist in its human host relies on numerous immune evasion strategies, such as the deregulation of the lipid metabolism leading to the formation of foamy macrophages (FM). Yet,… read more here.

Keywords: tuberculous pleural; transcription; mtb; formation ... See more keywords