Repurposing of Agrochemicals as ATTRv Amyloidosis Inhibitors.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.4c02221
Abstract: Transthyretin (TTR), a plasma protein, undergoes transformation into amyloid fibers, leading to ATTRv amyloidosis, a disease characterized by organ deposition of TTR amyloid fibrils and subsequent organ failure. Developing compounds that bind and kinetically stabilize… read more here.
Keywords: fibril formation; ttr; attrv amyloidosis; formation inhibition ... See more keywords
Interfacial Redox Chemistry–Driven Formation and Inhibition of Nanoparticles in Ultrasonic-Humidifier Microdroplets
Sign Up to like & getrecommendations! Published in 2025 at "Environmental Science: Nano"
DOI: 10.1039/d5en00741k
Abstract: Indoor air quality plays a critical role in human health, particularly due to prolonged exposure in enclosed environments. One major indoor air pollutant is fine particulate matter (PM 2.5), which... read more here.
Keywords: chemistry; driven formation; chemistry driven; redox chemistry ... See more keywords