Exploring the influence factors and improvement strategies of drug polymorphic transformation combined kinetic and thermodynamic perspectives during the formation of nanosuspensions.
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DOI: 10.1080/03639045.2022.2061988
Abstract: Nanosuspensions can effectively increase saturation solubility and improve the bioavailability of poorly water-soluble drugs attributed to high loading and surface-to-volume ratio. Wet media milling has been regarded as a scalable method to prepare nanosuspensions because… read more here.
Keywords: improvement strategies; influence factors; polymorphic transformation; transformation ... See more keywords