A Dual-Pronged Approach: A Ruthenium(III) Complex That Modulates Amyloid-β Aggregation and Disrupts Its Formed Aggregates.
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DOI: 10.1021/acs.inorgchem.1c01651
Abstract: Alzheimer's disease (AD) is a devastating neurological disorder for which soluble oligomers of the peptide amyloid-β (Aβ) are now recognized as the neurotoxic species. Metal-based therapeutics are uniquely suited to target Aβ, with ruthenium-based (Ru)… read more here.
Keywords: aggregation; based complexes; dual pronged; iii ... See more keywords