Mutant SOD1 aggregates formed in vitro and in cultured cells are polymorphic and differ from those arising in the CNS
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DOI: 10.1111/jnc.15718
Abstract: Mutations in the human Superoxide dismutase 1 (hSOD1) gene are well‐established cause of the motor neuron disease ALS. Patients and transgenic (Tg) ALS model mice carrying mutant variants develop hSOD1 aggregates in the CNS. We… read more here.
Keywords: cultured cells; cns; vitro cultured; aggregates formed ... See more keywords