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Induced Arp2/3 Complex Depletion Increases FMNL2/3 Formin Expression and Filopodia Formation

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Published in 2021 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2021.634708

Abstract: The Arp2/3 complex generates branched actin filament networks operating in cell edge protrusion and vesicle trafficking. Here we employ a conditional knockout mouse model permitting tissue- or cell-type specific deletion of the murine Actr3 gene… read more here.

Keywords: arp2 complex; filopodia; formin expression; formation ... See more keywords