Pore forming–mediated intracellular protein delivery for enhanced cancer immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Science Advances"
DOI: 10.1126/sciadv.abq4659
Abstract: Directly delivering therapeutic proteins to their intracellular targets remains a great challenge. Here, we apply CD8+ T cells to form pores on the tumor cells’ plasma membranes, enabling perfusion of ribonuclease A (RNase A) and… read more here.
Keywords: pore forming; protein delivery; mediated intracellular; forming mediated ... See more keywords