Bacterial Pore-Forming Toxins Promote the Activation of Caspases in Parallel to Necroptosis to Enhance Alarmin Release and Inflammation During Pneumonia
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-24210-8
Abstract: Pore-forming toxins are the most common virulence factor in pathogenic bacteria. They lead to membrane permeabilization and cell death. Herein, we show that respiratory epithelial cells (REC) undergoing bacterial pore-forming toxin (PFT)-induced necroptosis simultaneously experienced… read more here.
Keywords: caspase; forming toxins; necroptosis; pore forming ... See more keywords
Recent insights into mechanisms of cellular toxicity and cell recognition associated with the ABC family of pore-forming toxins.
Sign Up to like & getrecommendations! Published in 2023 at "Biochemical Society transactions"
DOI: 10.1042/bst20221409
Abstract: ABC toxins are pore-forming toxins characterised by the presence of three distinct components assembled into a hetero-oligomeric toxin complex ranging in size from 1.5-2.5 MDa. Most ABC toxins studied to date appear to be insecticidal toxins,… read more here.
Keywords: abc toxins; pore forming; cell; forming toxins ... See more keywords
Disarming Pore-Forming Toxins with Biomimetic Nanosponges in Intraocular Infections
Sign Up to like & getrecommendations! Published in 2019 at "mSphere"
DOI: 10.1128/msphere.00262-19
Abstract: Endophthalmitis is a blinding consequence of bacterial invasion of the interior of the eye. Because of increases in the numbers of ocular surgeries and intraocular injections, the incidence of endophthalmitis is steadily increasing. Staphylococcus aureus,… read more here.
Keywords: endophthalmitis; pathology; treatment; pore forming ... See more keywords
Neurotoxins and pore forming toxins in sea anemones: Potential candidates for new drug development.
Sign Up to like & getrecommendations! Published in 2022 at "Histology and histopathology"
DOI: 10.14670/hh-18-500
Abstract: There are two kinds of toxins in sea anemones: neurotoxins and pore forming toxins. As a representative of the sodium channel toxin, the neurotoxin ATX II in neurotoxin mainly affects the process of action potential… read more here.
Keywords: pore forming; neurotoxins pore; forming toxins; sea anemones ... See more keywords
Structural and Mechanistic Features of ClyA-Like α-Pore-Forming Toxins
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DOI: 10.3390/toxins10090343
Abstract: Recent technological advances have seen increasing numbers of complex structures from diverse pore-forming toxins (PFT). The ClyA family of α-PFTs comprises a broad variety of assemblies including single-, two- and three-component toxin systems. With crystal… read more here.
Keywords: toxins structural; forming toxins; structural mechanistic; pore forming ... See more keywords