Parent-Metabolite Pharmacokinetic Modeling of Formononetin and Its Active Metabolites in Rats after Oral Administration of Formononetin Formulations
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DOI: 10.3390/pharmaceutics15010045
Abstract: Formononetin is a major isoflavone contained in propolis and is reported to exhibit various pharmacological effects. However, the use of formononetin in pharmaceutical industry is limited due to its low bioavailability and solubility. There had… read more here.
Keywords: formononetin; formononetin active; oral administration; parent metabolite ... See more keywords
Formononetin, an Active Component of Astragalus Membranaceus, Inhibits the Pathogenesis and Progression of Esophageal Cancer Through the COX-2/Cyclin D1 Axis.
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DOI: 10.7754/clin.lab.2022.220403
Abstract: BACKGROUND The goal was to investigate the inhibitory effect of formononetin, an active component in Astragalus membranaceus, on the pathogenesis and development of esophageal cancer and the mechanism of action. METHODS The expression of COX-2… read more here.
Keywords: esophageal cancer; cox; formononetin active; pathogenesis ... See more keywords