A Randomized, Double-Blind, Double-Dummy Study of Glycopyrrolate/Formoterol Fumarate Metered Dose Inhaler Relative to Umeclidinium/Vilanterol Dry Powder Inhaler in COPD
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DOI: 10.1007/s12325-019-01015-3
Abstract: IntroductionGlycopyrrolate/formoterol fumarate metered dose inhaler (GFF MDI), formulated using co-suspension delivery technology, is the only approved fixed-dose combination long-acting muscarinic antagonist/long-acting β2-agonist (LAMA/LABA) delivered via MDI. Direct comparisons of GFF MDI versus other LAMA/LABAs have… read more here.
Keywords: gff mdi; inhaler; dpi; formoterol fumarate ... See more keywords
Pharmacokinetics and Tolerability of Budesonide/Glycopyrronium/Formoterol Fumarate Dihydrate and Glycopyrronium/Formoterol Fumarate Dihydrate Metered Dose Inhalers in Healthy Chinese Adults: A Randomized, Double-blind, Parallel-group Study.
Sign Up to like & getrecommendations! Published in 2019 at "Clinical therapeutics"
DOI: 10.1016/j.clinthera.2019.03.007
Abstract: PURPOSE The objective of this study was to assess pharmacokinetic (PK) and safety profiles of 2 fixed-dose combinations in development for the treatment of chronic obstructive pulmonary disease (COPD): budesonide/glycopyrronium/formoterol fumarate dihydrate metered-dose inhaler (BGF… read more here.
Keywords: formoterol; fumarate dihydrate; glycopyrronium; formoterol fumarate ... See more keywords
A phase III study of triple therapy with budesonide/glycopyrrolate/formoterol fumarate metered dose inhaler 320/18/9.6 μg and 160/18/9.6 μg using co-suspension delivery technology in moderate-to-very severe COPD: The ETHOS study protocol.
Sign Up to like & getrecommendations! Published in 2019 at "Respiratory medicine"
DOI: 10.1016/j.rmed.2019.08.010
Abstract: BACKGROUND Single inhaler triple therapies providing an inhaled corticosteroid, a long-acting muscarinic antagonist, and a long-acting β2-agonist (ICS/LAMA/LABAs) are an emerging treatment option for chronic obstructive pulmonary disease (COPD). Nevertheless, questions remain regarding the optimal… read more here.
Keywords: moderate severe; study; formoterol fumarate; severe copd ... See more keywords
Aclidinium bromide and formoterol fumarate for the maintenance treatment of chronic obstructive pulmonary disease
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Clinical Pharmacology"
DOI: 10.1080/17512433.2020.1717334
Abstract: ABSTRACT Introduction: Treatment options for COPD have evolved rapidly in the last decade and inhaled bronchodilators have largely supplanted the use of oral bronchodilators because of their increased efficacy and excellent safety with topical delivery… read more here.
Keywords: aclidinium; bromide formoterol; treatment; formoterol fumarate ... See more keywords
Lung Deposition of Inhaled Extrafine Beclomethasone Dipropionate/Formoterol Fumarate/Glycopyrronium Bromide in Healthy Volunteers and Asthma: The STORM Study
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Aerosol Medicine and Pulmonary Drug Delivery"
DOI: 10.1089/jamp.2021.0046
Abstract: Background: An extrafine formulation triple therapy combination of beclomethasone dipropionate (BDP), formoterol fumarate (FF), and glycopyrronium bromide (GB) has been developed for the maintenance treatment of asthma and chronic obstructive pulmonary disease. This study used… read more here.
Keywords: healthy volunteers; formoterol fumarate; lung; deposition ... See more keywords
A comparison of the efficacy and safety of combined aclidinium bromide and formoterol fumarate in the treatment of chronic obstructive pulmonary disease
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DOI: 10.1097/md.0000000000021856
Abstract: Abstract Background: To systematically evaluate the efficacy and safety of combined aclidinium bromide and formoterol fumarate for chronic obstructive pulmonary disease (COPD). Methods: Electronic databases including PubMed, MEDLINE, EMBASE, Cochrane Library Central Register of Controlled… read more here.
Keywords: combined aclidinium; bromide formoterol; aclidinium bromide; formoterol fumarate ... See more keywords
Functional respiratory imaging assessment of glycopyrrolate and formoterol fumarate metered dose inhalers formulated using co-suspension delivery technology in patients with COPD
Sign Up to like & getrecommendations! Published in 2020 at "Therapeutic Advances in Respiratory Disease"
DOI: 10.1177/1753466620916990
Abstract: Background: Functional respiratory imaging (FRI) is a quantitative postprocessing imaging technique used to assess changes in the respiratory system. Using FRI, we characterized the effects of the long-acting muscarinic antagonist (LAMA), glycopyrrolate metered dose inhaler… read more here.
Keywords: metered dose; respiratory imaging; mdi; functional respiratory ... See more keywords
Effect of inhaled budesonide/formoterol fumarate dihydrate delivered via two different devices on lung function in patients with COPD and low peak inspiratory flow
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DOI: 10.1177/17534666221107312
Abstract: Background and aims: Low peak inspiratory flow (PIF) is common following severe exacerbations of chronic obstructive pulmonary disease (COPD). Patients with COPD and low PIF may be at risk of suboptimal delivery of inhaled therapies… read more here.
Keywords: fumarate dihydrate; formoterol fumarate; lung function; week ... See more keywords
Beclomethasone dipropionate and formoterol fumarate synergistically interact in hyperresponsive medium bronchi and small airways
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DOI: 10.1186/s12931-018-0770-7
Abstract: BackgroundCorticosteroids increase the expression of β2-adrenoceptors (β2-ARs) and protect them against down-regulation. Conversely, β2-AR agonists improve the anti-inflammatory action of corticosteroids. Nevertheless, it is still uncertain whether adding a long-acting β2-AR agonist (LABA) to an… read more here.
Keywords: small airways; combination; medium; interaction ... See more keywords
Validation of Novel Analytical RP-HPLC Method for determination of Formoterol Fumarate and Budesonide in Inhalation Suspension Pharmaceutical Dosage Form
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DOI: 10.52711/0974-360x.2021.00761
Abstract: Formoterol Fumarate and Budesonide inhalation suspension is prescribed for treatment of Asthmatic patient. Formoterol Fumarate is anti-asthmatic drug (Bronchodilator) and Budesonide is Anti Inflammatory Drug (Glucocortico steroid) drug. A bronchodilator is a substance that dilates… read more here.
Keywords: formoterol; method; fumarate budesonide; budesonide inhalation ... See more keywords