Science and Art of Protein Formulation Development.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2019.118505
Abstract: Protein pharmaceuticals have become a significant class of marketed drug products and are expected to grow steadily over the next decade. Development of a commercial protein product is, however, a rather complex process. A critical… read more here.
Keywords: art protein; formulation development; science art; development ... See more keywords
Maximising success in multidrug formulation development: A review
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.05.024
Abstract: &NA; Patient compliance will soon become one of the most critical challenges in modern healthcare. Due in part to our aging population, the rise in the number of chronic conditions will cause increasing stress on… read more here.
Keywords: formulation; formulation development; multidrug formulation; success multidrug ... See more keywords
Predictive Screening Tools Used in High-Concentration Protein Formulation Development.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2017.10.036
Abstract: This review examines the use of predictive screening approaches in high-concentration protein formulation development. In addition to the normal challenges associated with protein formulation development, for high-concentration formulations, solubility, viscosity, and physical protein degradation play… read more here.
Keywords: protein formulation; high concentration; formulation; formulation development ... See more keywords
Formulation development, in vitro and in vivo evaluation of chitosan engineered nanoparticles for ocular delivery of insulin
Sign Up to like & getrecommendations! Published in 2020 at "RSC Advances"
DOI: 10.1039/d0ra07640f
Abstract: Insulin-dependent diabetic patients have to count on the administration of painful and discomforting insulin injections. However, inadequate insulin absorption and the risk of insulin level escalation in the blood are some disadvantages associated with insulin… read more here.
Keywords: insulin; vivo; insulin loaded; development vitro ... See more keywords
Formulation Development and Pharmaceutical Evaluation of Lysiphyllum strychnifolium Topical Patches for Their Anti-inflammatory Potential
Sign Up to like & getrecommendations! Published in 2022 at "AAPS PharmSciTech"
DOI: 10.1208/s12249-022-02269-x
Abstract: Topical drug delivery systems are interesting and popular dosage forms for formulation development. Thai herbs are used in alternative medicine to treat patients suffering from severe illnesses. They have significant economic and cultural value in… read more here.
Keywords: herbal topical; thai herbal; formulation development; topical patches ... See more keywords
Molecular Docking in Formulation and Development.
Sign Up to like & getrecommendations! Published in 2019 at "Current drug discovery technologies"
DOI: 10.2174/1570163815666180219112421
Abstract: BACKGROUND In pharmaceutical research drug discovery and development process is timeconsuming and expensive. In many cases, it produces incompetent results due to the failure of in vitro and in vivo conventional approaches. Before any new… read more here.
Keywords: drug; formulation development; drug discovery; development ... See more keywords
FORMULATION AND DEVELOPMENT OF TOPICAL ANTI ACNE FORMULATION OF SPIRULINA EXTRACT
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Applied Pharmaceutics"
DOI: 10.22159/ijap.2018v10i6.26334
Abstract: Objective: The objective of this research was to formulate and evaluate anti-acne ointment of C-phycocyanin(C-PC) extracted from spirulina.Methods: C-PC was successfully extracted from spirulina by using sonication and cold-maceration process and further purified by dialysis… read more here.
Keywords: formulation; formulation development; development topical; anti acne ... See more keywords
Formulation Development of Sublingual Cyclobenzaprine Tablets Empowered by Standardized and Physiologically Relevant Ex Vivo Permeation Studies
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13091409
Abstract: Suitable ex vivo models are required as predictive tools of oromucosal permeability between in vitro characterizations and in vivo studies in order to support the development of novel intraoral formulations. To counter a lack of… read more here.
Keywords: vivo; permeation; formulation development; model ... See more keywords
Formulation Development and Optimization of Tramadol Hydrochloride Fast Dissolving Tablets with Natural Superdisintegrant
Sign Up to like & getrecommendations! Published in 2019 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2019.00935.1
Abstract: Tramadol is an opoid medication used to treat moderate to severe pain. The onset of pain relief begins usually within an hour of administration. In the present study an attempt has been made to develop… read more here.
Keywords: natural superdisintegrant; tramadol; fast dissolving; formulation development ... See more keywords