Design of Experiment Approach to Modeling the Effects of Formulation and Drug Loading on the Structure and Properties of Therapeutic Nanogels
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.1c00699
Abstract: The physical properties of nanoparticles may affect the uptake mechanism, biodistribution, stability, and other physicochemical properties of drug delivery systems. This study aimed to first develop a model exploring the factors controlling the nanogel physical… read more here.
Keywords: structure; drug loading; formulation drug; drug ... See more keywords
A carbohydrate polymer is a critical variable in the formulation of drug nanocrystals: a case study of idebenone
Sign Up to like & getrecommendations! Published in 2019 at "Expert Opinion on Drug Delivery"
DOI: 10.1080/17425247.2019.1682546
Abstract: ABSTRACT Objective: Stabilizers, especially carbohydrate polymers, have been shown to be necessary for the stabilization of drug nanocrystals. However, the impacts of select stabilizers on the in vitro and in vivo efficacy of therapeutics have… read more here.
Keywords: formulation drug; idbnc; study; drug ... See more keywords