Origins, and formulation implications, of the pKa difference between boronic acids and their esters: A density functional theory study
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DOI: 10.1016/j.ejps.2018.08.017
Abstract: ABSTRACT The purpose of this study is to try to identify the etiology and formulation implications of the significant pKa drop in aqueous solution that occurs when boronic acids are reversibly esterified by reaction with… read more here.
Keywords: density functional; boronic acids; formulation implications; functional theory ... See more keywords