Formulation, optimization, hemocompatibility and pharmacokinetic evaluation of PLGA nanoparticles containing paclitaxel
Sign Up to like & getrecommendations! Published in 2019 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2018.1542706
Abstract: Abstract Objective: Paclitaxel (PTX)-loaded polymer (Poly(lactic-co-glycolic acid), PLGA)-based nanoformulation was developed with the objective of formulating cremophor EL-free nanoformulation intended for intravenous use. Significance: The polymeric PTX nanoparticles free from the cremophor EL will help… read more here.
Keywords: ptx; formulation; formulation optimization; hemocompatibility ... See more keywords
Formulation, optimization, and evaluation of raft-forming formulations containing Nizatidine
Sign Up to like & getrecommendations! Published in 2019 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2019.1569033
Abstract: Abstract Objective: The main objective of this research is to formulate, optimize, and evaluate raft-forming chewable tablets of Nizatidine. Various raft-forming agents were used in preliminary screening. Sodium alginate showed maximum raft strength, so tablets… read more here.
Keywords: raft forming; raft; drug; formulation optimization ... See more keywords
Formulation optimization of smart thermosetting lamotrigine loaded hydrogels using response surface methodology, box benhken design and artificial neural networks
Sign Up to like & getrecommendations! Published in 2020 at "Drug Development and Industrial Pharmacy"
DOI: 10.1080/03639045.2020.1791163
Abstract: Abstract The aim of this research was to develop lamotrigine containing thermosetting hydrogel for intranasal administration to manage and treat generalized epilepsy. Thermosetting hydrogels were prepared using different ratios of poloxamer 407 (L127), poloxamer 188… read more here.
Keywords: methodology; formulation optimization; box; lamotrigine ... See more keywords
Bedaquiline fumarate microemulsion: formulation optimization, rheological characterization and in vitro studies.
Sign Up to like & getrecommendations! Published in 2022 at "Nanomedicine"
DOI: 10.2217/nnm-2022-0132
Abstract: Aim: Bedaquiline fumarate (BQF), an antitubercular drug, shows limited bioavailability due to solubility-limited intestinal absorption. In this research, the authors formulated a BQF-loaded microemulsion to improve BQF's oral bioavailability. Methods: Microemulsion was prepared by a spontaneous emulsification method… read more here.
Keywords: bedaquiline fumarate; microemulsion; microemulsion formulation; formulation optimization ... See more keywords
Formulation and Optimization of Repaglinide Nanoparticles Using Microfluidics for Enhanced Bioavailability and Management of Diabetes
Sign Up to like & getrecommendations! Published in 2023 at "Biomedicines"
DOI: 10.3390/biomedicines11041064
Abstract: The technologies for fabrication of nanocrystals have an immense potential to improve solubility of a variety of the poor water-soluble drugs with subsequent enhanced bioavailability. Repaglinide (Rp) is an antihyperglycemic drug having low bioavailability due… read more here.
Keywords: repaglinide nanoparticles; optimization repaglinide; formulation optimization; nanoparticles using ... See more keywords
Addendum: Gilani et al. Formulation and Optimization of Nano Lipid Based Oral Delivery Systems for Arthritis. Coatings 2021, 11, 548
Sign Up to like & getrecommendations! Published in 2021 at "Coatings"
DOI: 10.3390/coatings11070781
Abstract: The authors wish to make the following corrections to this paper [...] read more here.
Keywords: gilani formulation; lipid based; formulation optimization; nano lipid ... See more keywords
Formulation and Optimization of Avanafil Biodegradable Polymeric Nanoparticles: A Single-Dose Clinical Pharmacokinetic Evaluation
Sign Up to like & getrecommendations! Published in 2020 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics12060596
Abstract: Avanafil (AVA) is a second-generation phosphodiesterase-5 (PDE5) inhibitor. AVA shows high selectivity to penile tissues and fast absorption, but has a bioavailability of about 36%. The aim was to formulate and optimize AVA-biodegradable nanoparticles (NPs)… read more here.
Keywords: formulation; formulation optimization; avanafil biodegradable; ava ... See more keywords
Mini-Review of Self-Healing Mechanism and Formulation Optimization of Polyurea Coating
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14142808
Abstract: Self-healing polymers are categorized as smart materials that are capable of surface protection and prevention of structural failure. Polyurethane/polyurea, as one of the representative coatings, has also attracted attention for industrial applications. Compared with polyurethane,… read more here.
Keywords: self; self healing; formulation optimization; polyurea coating ... See more keywords