Formulation strategies for mitigating dissolution reduction of p-aminobenzoic acid by sodium lauryl sulfate through diffusion layer modulation.
Sign Up to like & getrecommendations! Published in 2021 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2021.121310
Abstract: The use of the surfactant, sodium lauryl sulfate (SLS), instead of enhancing drug dissolution, deteriorates the dissolution of some alkaline drugs through forming poorly soluble lauryl sulfate salts. The thermodynamic driving force for precipitation of… read more here.
Keywords: lauryl sulfate; aminobenzoic acid; strategies mitigating; sodium lauryl ... See more keywords
Advanced engineering of third-generation lysins and formulation strategies for clinical applications
Sign Up to like & getrecommendations! Published in 2020 at "Critical Reviews in Microbiology"
DOI: 10.1080/1040841x.2020.1809346
Abstract: Abstract One of the possible solutions for the current antibiotic resistance crisis may be found in (often bacteriophage-derived) peptidoglycan hydrolases. The first clinical trials of these natural enzymes, coined here as first-generation lysins, are currently… read more here.
Keywords: formulation strategies; generation; engineering; third generation ... See more keywords
Formulation Strategies to Improve Oral Bioavailability of Ellagic Acid
Sign Up to like & getrecommendations! Published in 2020 at "Applied Sciences"
DOI: 10.3390/app10103353
Abstract: Ellagic acid, a polyphenolic compound present in fruit and berries, has recently been the object of extensive research for its antioxidant activity, which might be useful for the prevention and treatment of cancer, cardiovascular pathologies,… read more here.
Keywords: bioavailability; formulation strategies; ellagic acid; improve oral ... See more keywords
Formulation Strategies for Improving the Stability and Bioavailability of Vitamin D-Fortified Beverages: A Review
Sign Up to like & getrecommendations! Published in 2022 at "Foods"
DOI: 10.3390/foods11060847
Abstract: Vitamin D is a lipophilic bioactive that plays an important role in bone health. Fortification of beverages, such as milk, fruit juices, teas, and vegetable drinks, could be an efficient strategy to prevent vitamin D… read more here.
Keywords: stability bioavailability; formulation strategies; strategies improving; vitamin ... See more keywords
Formulation Strategies to Improve the Stability and Handling of Oral Solid Dosage Forms of Highly Hygroscopic Pharmaceuticals and Nutraceuticals
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14102015
Abstract: Highly hygroscopic pharmaceutical and nutraceutical solids are prone to significant changes in their physicochemical properties due to chemical degradation and/or solid-state transition, resulting in adverse effects on their therapeutic performances and shelf life. Moisture absorption… read more here.
Keywords: formulation strategies; highly hygroscopic; solid dosage; hygroscopic pharmaceuticals ... See more keywords
Embedding of Poorly Water-Soluble Drugs in Orodispersible Films—Comparison of Five Formulation Strategies
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15010017
Abstract: The poor bioavailability of many newly developed active pharmaceutical ingredients (APIs) poses a major challenge in formulation development. To overcome this issue, strategies such as the preparation of amorphous solid dispersions (ASDs), and the application… read more here.
Keywords: poorly water; orodispersible films; formulation; formulation strategies ... See more keywords
Formulation Strategies of Nanosuspensions for Various Administration Routes
Sign Up to like & getrecommendations! Published in 2023 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics15051520
Abstract: Nanosuspensions (NSs), which are nanosized colloidal particle systems, have recently become one of the most interesting substances in nanopharmaceuticals. NSs have high commercial potential because they provide the enhanced solubility and dissolution of low-water-soluble drugs… read more here.
Keywords: administration; administration routes; formulation strategies; strategies nanosuspensions ... See more keywords
Formulation Strategies for Enhancing Pharmaceutical and Nutraceutical Potential of Sesamol: A Natural Phenolic Bioactive
Sign Up to like & getrecommendations! Published in 2023 at "Plants"
DOI: 10.3390/plants12051168
Abstract: Natural plants and their products continue to be the major source of phytoconstituents in food and therapeutics. Scientific studies have evidenced the benefits of sesame oil and its bioactives in various health conditions. Various bioactives… read more here.
Keywords: sesamol; enhancing pharmaceutical; formulation strategies; pharmaceutical nutraceutical ... See more keywords