Preparation and Application of an Inexpensive α-Formylglycine Building Block Compatible with Fmoc Solid-Phase Peptide Synthesis
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DOI: 10.1021/acs.orglett.2c04059
Abstract: α-Formylglycine (fGly) is a rare residue located in the active site of sulfatases and serves as a precursor to pharmaceutically relevant motifs. The installation of fGly motifs into peptides is currently challenging due to degradation… read more here.
Keywords: synthesis; peptide synthesis; solid phase; formylglycine building ... See more keywords