Oxygen Activation by a Copper Complex with Sulfur-Only Coordination Relevant to the Formylglycine Generating Enzyme.
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DOI: 10.1021/acs.inorgchem.2c00746
Abstract: Synthesizing hydrosulfido Cu thiolate complexes is quite challenging. In this report, two new and rare hydrosulfido Cu thiolate complexes, [Et4N]2[(mnt)Cu-SH] (2, mnt = maleonitrile dithiolene = S2C2(CN)2) and [Et4N]3[(mnt)Cu-(μ-SH)-Cu(mnt)] (3), have been synthesized. Coordination sites… read more here.
Keywords: coordination; spectroscopy; chemistry; sulfur ... See more keywords
The discovery of penta-peptides inhibiting the activity of the formylglycine-generating enzyme and their potential antibacterial effects against Mycobacterium tuberculosis
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DOI: 10.1039/d2ra03379h
Abstract: The formylglycine-generating enzyme is a key regulator that converts sulfatase into an active form. Despite its key role in many diseases, enzyme activity inhibitors have not yet been reported. In this study, we investigated penta-peptide… read more here.
Keywords: effects mycobacterium; generating enzyme; formylglycine generating; potential antibacterial ... See more keywords