Mutagenic and teratogenic toxicity evaluation of Forsythia suspensa leaves aqueous extract.
Sign Up to like & getrecommendations! Published in 2021 at "Drug and chemical toxicology"
DOI: 10.1080/01480545.2021.1883645
Abstract: Forsythia suspensa leaves (FSL), rich in phillyrin, forsythiaside A, phillygenin, rutin, and other compounds, is a known traditional Chinese medicine (TCM). It has been effective in heat retreat and detoxification. In this study, we performed… read more here.
Keywords: toxicity evaluation; suspensa leaves; toxicity; teratogenic toxicity ... See more keywords
New lignans and phenylethanoid with antioxidant activity from aerial parts of Forsythia suspensa (Thunb.) Vahl
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DOI: 10.1080/14786419.2022.2087650
Abstract: Abstract Two new lignans, phillyroside A(1) and phillyroside B(2), together with three new phenylethanoid glycoside, forsythoside K(3), forsythoside L(5) and forsythol L (4), while compounds 4 was an aglycon of forsythoside L(5), were isolated from… read more here.
Keywords: forsythia suspensa; antioxidant activity; new lignans; aerial parts ... See more keywords
Metabolome analysis of genus Forsythia related constituents in Forsythia suspensa leaves and fruits using UPLC-ESI-QQQ-MS/MS technique
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DOI: 10.1371/journal.pone.0269915
Abstract: Forsythia suspensa is a traditional Chinese herb. Its numerous metabolites have important roles, as they possessed a wide range of biological activities. This study explored the accumulations of F. suspensa metabolites by performing widely targeted… read more here.
Keywords: forsythia suspensa; forsythia related; leaves fruits; forsythia ... See more keywords
Comparative Transcriptome Analysis of MeJA Responsive Enzymes Involved in Phillyrin Biosynthesis of Forsythia suspensa
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DOI: 10.3390/metabo12111143
Abstract: Forsythia suspensa (Thunb.) has been widely used in traditional medicines in Asia. According to the 2020 edition of Chinese Pharmacopoeia, phillyrin is the main active ingredient in F. suspensa, which is effective in clearing heat,… read more here.
Keywords: meja; forsythia suspensa; phillyrin biosynthesis; biosynthesis ... See more keywords
Quickly Identifying High-Risk Variables of Ultrasonic Extraction Oil from Multi-Dimensional Risk Variable Patterns and a Comparative Evaluation of Different Extraction Methods on the Quality of Forsythia suspensa Seed Oil
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DOI: 10.3390/molecules24193445
Abstract: Generally, essential oils and components of interest are extracted from plants using organic solvent, distillation, ultrasound and supercritical extraction methods. Ultrasonic extraction (UE) has the advantage of high efficiency, but its process is complicated and… read more here.
Keywords: extraction; risk; seed; suspensa seed ... See more keywords
Green Extraction of Forsythoside A, Phillyrin and Phillygenol from Forsythia suspensa Leaves Using a β-Cyclodextrin-Assisted Method
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DOI: 10.3390/molecules27207055
Abstract: In this study, a green process of β-cyclodextrin (β-CD)-assisted extraction of active ingredients from Forsythia suspensa leaves was developed. Firstly, the optimal process of extraction was as follows: the ratio between Forsythia suspensa leaves and… read more here.
Keywords: forsythia suspensa; extraction; cyclodextrin assisted; forsythoside phillyrin ... See more keywords
Forsythia suspensa Protects against Bone Loss in Ovariectomized Mice
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DOI: 10.3390/nu11081831
Abstract: In traditional oriental medicine, the fruit of Forsythia suspensa has been used as a nutritional supplement to alleviate inflammation and treat gastrointestinal diseases. However, there is no information available on its beneficial effects on bone.… read more here.
Keywords: forsythia suspensa; bone; osteoclast differentiation; bone loss ... See more keywords